Performance evaluation of a compact PET/SPECT/CT tri-modality system for small animal imaging applications
Performance evaluation of a compact PET/SPECT/CT tri-modality system for small animal imaging applications
复制标题
用于小动物成像应用的紧凑型 PET/SPECT/CT 三模态系统的性能评估
DOI：
10.1016/j.nima.2015.03.045
复制
发表时间：
2015-06
影响因子：
1.4
通讯作者：
Liu, Yaqiang
中科院分区：
文献类型：
--
作者：
Xia, Yan;Fan, Peng;Lyu, Zhenlei;Liu, Yaqiang
PET, SPECT and CT imaging techniques are widely used in preclinical small animal imaging applications. In this paper, we present a compact small animal PET/SPECT/CT tri-modality system. A dual-functional, shared detector design is implemented which enables PET and SPECT imaging with a same LYSO ring detector. A multi-pinhole collimator is mounted on the system and inserted into the detector ring in SPECT imaging mode. A cone-beam CT consisting of a micro focus X-ray tube and a CMOS detector is implemented. The detailed design and the performance evaluations are reported in this paper. In PET imaging mode, the measured NEMA based spatial resolution is 2.12 mm (FWHM), and the sensitivity at the central field of view (CFOV) is 3.2%. The FOV size is 50 mm (∅)×100 mm (L). The SPECT has a spatial resolution of 1.32 mm (FWHM) and an average sensitivity of 0.031% at the center axial, and a 30 mm (∅)×90 mm (L) FOV. The CT spatial resolution is 8.32 lp/mm @10%MTF, and the contrast discrimination function value is 2.06% with 1.5 mm size cubic box object. In conclusion, a compact, tri-modality PET/SPECT/CT system was successfully built with low cost and high performance.
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DOI：
10.1109/nssmic.2013.6829743
发表时间：
2013-10
期刊：
2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC)
影响因子：
--
作者：
Zhenlei Lv;G. Gong;Shuai Huang;Yaqiang Liu
通讯作者：
Zhenlei Lv;G. Gong;Shuai Huang;Yaqiang Liu
DOI：
10.1109/nssmic.2012.6551636
发表时间：
2012-10
期刊：
2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)
影响因子：
--
作者：
Jing Wu;Tianyu Ma;Hui Liu;Yan Xia;Si Chen;Shi Wang;Yaqiang Liu;Jianping Cheng
通讯作者：
Jing Wu;Tianyu Ma;Hui Liu;Yan Xia;Si Chen;Shi Wang;Yaqiang Liu;Jianping Cheng
DOI：
10.1109/nssmic.2013.6829237
发表时间：
2013-10
期刊：
2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC)
影响因子：
--
作者：
Yu Yunhan;Yan Xia;Wei Wang;Yaqiang Liu;K. Ying;Shi Wang;Tianyu Ma
通讯作者：
Yu Yunhan;Yan Xia;Wei Wang;Yaqiang Liu;K. Ying;Shi Wang;Tianyu Ma
影响因子：
3.8
作者：
Sanchez, F.;Orero, A.;Leevy, W. M.
通讯作者：
Leevy, W. M.
DOI：
10.13538/j.1001-8042/nst.22.224-229
发表时间：
2011
期刊：
--
影响因子：
--
作者：
Wei Qingyang;Wang Shi;Ma Tianyu;Ma Fei;Dai Tiantian;Xu Tianpeng;Wu Zhaoxia;Jin Yongjie;Li Yaqiang
通讯作者：
Wei Qingyang;Wang Shi;Ma Tianyu;Ma Fei;Dai Tiantian;Xu Tianpeng;Wu Zhaoxia;Jin Yongjie;Li Yaqiang