A sutureless method for digestive tract reconstruction during pancreaticoduodenectomy in a dog model.
A sutureless method for digestive tract reconstruction during pancreaticoduodenectomy in a dog model.
复制标题
一种在犬模型胰十二指肠切除术中进行消化道重建的无缝方法。
DOI：
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发表时间：
2015-01
期刊：
影响因子：
--
通讯作者：
Wu Z
中科院分区：
文献类型：
--
作者：
Lei P;Liu S;Liu X;Wu Z
未标记
胰瘘是胰管切除术后的主要并发症，可导致术后死亡。因此，需要更安全和更有效的吻合方法来避免泄漏和降低死亡率。
材料和方法
使用20只体重范围为15 - 25 kg的家犬，不分性别。在这些狗中手术制备胆总管和胰管扩张模型。通过测定血清淀粉酶、并发症发生率和生存时间，研究了胰胆支架联合磁性支架（PB-MA）和纤维蛋白胶治疗的疗效。
结果
建立纤维蛋白胶胰肠吻合所需的平均时间为9 ± 2.05 min，而建立磁性胆肠吻合所需的平均时间为5 ± 0.9 min。总手术时间为2.7 ± 0.6 h。接受手术的狗中有80%在手术后15天内仍然活着，没有一只发生胰瘘。大体观察及病理标本苏木精-伊红染色检查表明，骨折完全愈合。
结论
PB-MA在胰腺切除术的无缝线消化道重建中的使用消除了胰瘘，缩短了支架取出时间。此外，该程序执行简单，快速，并且在该犬模型中似乎是安全的。
UNLABELLED
Development of pancreatic fistulas as a result of anastomotic gaps is still a major complication after pancreaticoduodenectomy, and can cause post-operative death. Therefore, safer and more effective methods of anastomosis are needed to avoid leakage and decrease mortality.
MATERIALS AND METHODS
Twenty domestic dogs with body weights ranging from 15 to 25 kg were used, regardless of gender. A model of common bile duct and pancreatic duct dilatation was surgically prepared in these dogs. Pancreaticobiliary stents combined with magnetic anastomoses (PB-MA), and controls were treated with fibrin glue were studied in terms of and efficacy by measurement of serum amylase, incidence of complications, and survival times.
RESULTS
The mean time required to create the fibrin glue pancreaticoenterostomy was 9 ± 2.05 min, while the mean time required to create the magnet cholangioenterostomy was 5 ± 0.9 min. The total operative time was 2.7 ± 0.6 h. Eighty percent of the dogs that underwent the operations were still alive for 15 days after the operations and none developed pancreatic fistulas. Examination by macroscopic observation, and hematoxylin and eosin staining of the pathological specimens showed that the anastomoses were completed healed.
CONCLUSIONS
The use of a PB-MA in sutureless digestive tract reconstruction for pancreatoduodenectomy resulted in an elimination of pancreatic fistulas, and shortening of the stent removed time. In addition, the procedure is simple to perform, fast, and appears to be safe in this dog model.
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DOI：
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发表时间：
1999-03
期刊：
Chirurgia italiana
影响因子：
--
作者：
R. Cirocchi;P. Covarelli;M. Mazieri;B. Fabbri;C. Bisacci;C. Fabbri;R. Bisacci
通讯作者：
R. Cirocchi;P. Covarelli;M. Mazieri;B. Fabbri;C. Bisacci;C. Fabbri;R. Bisacci
影响因子：
3.2
作者：
S. Peng;Y. Mou;Yin Bin Liu;Ying Su;C. Peng;X. Cai;Yu Lian Wu;L. Zhou
通讯作者：
S. Peng;Y. Mou;Yin Bin Liu;Ying Su;C. Peng;X. Cai;Yu Lian Wu;L. Zhou
DOI：
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发表时间：
2006
期刊：
Journal of the Fourth Military Medical University
影响因子：
--
作者：
Zhang Yong
通讯作者：
Zhang Yong
影响因子：
7.7
作者：
P. Jamidar;M. Cadeddu;A. Mosse;C. Swain
通讯作者：
P. Jamidar;M. Cadeddu;A. Mosse;C. Swain
影响因子：
2.9
作者：
Satoi, Sohei;Toyokawa, Hideyoshi;Kwon, A-Hon
通讯作者：
Kwon, A-Hon