Prevalence and incidence of gallstones in liver cirrhosis.
Prevalence and incidence of gallstones in liver cirrhosis.
复制标题
肝硬化胆结石的患病率和发病率。
DOI:
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复制
发表时间:
1997
影响因子:
1.9
通讯作者:
J. Rodrigo
中科院分区:
文献类型:
--
作者:
J. D. Del Olmo;F. García;M. Serra;L. Maldonado;J. Rodrigo
BACKGROUND
Our aim was to assess the prevalence and incidence of gallstone disease in patients with liver cirrhosis and to identify risk factors for cholecystolithiasis.
METHODS
We studied a cohort of 313 patients with liver cirrhosis confirmed by histology and/or laparoscopy and 357 patients free of liver disease, who had been referred for ultrasonographic examination of the upper abdomen. Hepatobiliary ultrasonography was performed when liver cirrhosis was diagnosed and every 6 months thereafter. Risk factors for cholelithiasis (age, gender, diet, pregnancy, diabetes, family history of cholelithiasis, etiology of cirrhosis, decompensated disease) were assessed.
RESULTS
The overall prevalence of gallstones in cirrhotic patients was 23.3%. In controls, the overall prevalence of cholecystolithiasis was 16.8%. After a median follow-up period of 65 months, 30 patients developed gallstones. The calculated annual incidence was 3.4%.
CONCLUSIONS
Given that the prevalence of gallstone disease is higher in cirrhotics than in noncirrhotic patients, cirrhosis of the liver may be considered a risk factor for cholecystolithiasis.
DOI:
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发表时间:
1990
期刊:
Hepatology (Baltimore, Md.)
影响因子:
--
作者:
Ostrow,JD
通讯作者:
Ostrow,JD