Patients with large myocardial infarction gain a greater improvement in exercise capacity after exercise training than those with small to medium infarction

Patients with large myocardial infarction gain a greater improvement in exercise capacity after exercise training than those with small to medium infarction
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DOI:
10.1002/clc.4950260608
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发表时间:
2003-06-01
影响因子:
2.7
通讯作者:
Goto, Y
Goto, Y
中科院分区:
医学3区
文献类型:
--
作者:
Sakuragi, S;Takagi, S;Goto, Y

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背景:大面积心肌梗死患者运动训练能否获得与中小面积心肌梗死患者相同的效益尚不清楚。假设:本研究旨在探讨心脏康复治疗后大面积心肌梗死患者运动能力改善的幅度和机制。方法:将296例急性心肌梗死后参加心脏康复治疗的患者根据血清肌酸磷酸激酶峰值水平分为两组:大梗死组(第1组)(大于或等于5000U/L峰值CPK),患者)和面积较小的梗死组(第2组)(
Background: It remains unclear whether patients with large-size myocardial infarction (MI) achieve the same benefit from exercise training as do those with small- to medium-size MI.Hypothesis: This study was designed to determine the magnitude and mechanisms underlying improvement in exercise capacity in patients with large-size MI after cardiac rehabilitation.Methods: In all, 296 patients who participated in a cardiac rehabilitation program after acute MI were divided into two groups according to the peak serum creatine phosphokinase (CPK) level: the group with large infarction (Group 1) (greater than or equal to 5000 U/l peak CPK, 64 patients) and the group with less extensive infarction (Group 2) (