National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study
National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study
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DOI：
10.1136/bmj.m1590
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发表时间：
2020-05-28
影响因子：
105.7
通讯作者：
Ashcroft, Darren M.
中科院分区：
文献类型：
--
作者：
Parisi, Rosa;Iskandar, Ireny Y. K.;Ashcroft, Darren M.
目的系统回顾并提供有关银屑病发病率的信息，并对全球、区域和国家的患病率进行量化估计。设计系统回顾和荟萃分析。数据源系统地检索了 Medline、Embase、Web of Science、SciELO、韩国期刊数据库、俄罗斯科学引文索引、WPRIM、SaudiMedlit、Informit、IndMed 和 HERDIN。 起始日期截至 2019 年 10 月。方法如果报告了普通人群中银屑病的发病率或患病率，则纳入研究。发病率数据进行了描述性总结，而贝叶斯分层模型则用于估计全球、区域和国家特定的银屑病患病率。结果41 确定了 164 条记录，168 项研究符合纳入标准。在成人中，银屑病的发病率从台湾每 10 万人年 30.3 例（95% 置信区间 26.6 至 34.1）到意大利每 10 万人年 321.0 例不等。银屑病的患病率从东亚的 0.14%（95% 不确定性区间为 0.05% 至 0.40%）到澳大利亚的 1.99%（0.64% 至 6.60%）不等。西欧（1.92%、1.07%至3.46%）、中欧（1.83%、0.62%至5.32%）、北美（1.50%、0.63%至3.60%）和高收入拉丁美洲南部（1.10%、0.36%至3.60%）的银屑病患病率也很高。 2.96%）。结论世界上 81% 的国家缺乏有关流行病学的信息 银屑病。这种疾病在成人中比在儿童中更常见。牛皮癣在不同地理区域的分布不均；这种情况在高收入国家和人口老龄化地区更为常见。所提供的估计值可以帮助指导各国和国际社会就银屑病的适当管理做出公共卫生决策并评估其随着时间的推移的自然史。
OBJECTIVETo systematically review and provide information on the incidence of psoriasis and quantify global, regional, and country specific estimates of its prevalence.DESIGNSystematic review and meta-analysis.DATA SOURCESMedline, Embase, Web of Science, SciELO, Korean Journal Databases, Russian Science Citation Index, WPRIM, SaudiMedlit, Informit, IndMed, and HERDIN were searched systematically from their inception dates to October 2019.METHODSStudies were included if they reported on the incidence or prevalence of psoriasis in the general population. Incidence data were summarised descriptively, whereas bayesian hierarchical models were fitted to estimate the global, regional, and country specific prevalence of psoriasis.RESULTS41 164 records were identified and 168 studies met the inclusion criteria. In adults, the incidence of psoriasis varied from 30.3 per 100000 person years (95% confidence interval 26.6 to 34.1) in Taiwan to 321.0 per 100 000 person years in Italy. The prevalence of psoriasis varied from 0.14% (95% uncertainty interval 0.05% to 0.40%) in east Asia to 1.99% (0.64% to 6.60%) in Australasia. The prevalence of psoriasis was also high in western Europe (1.92%, 1.07% to 3.46%), central Europe (1.83%, 0.62% to 5.32%), North America (1.50%, 0.63% to 3.60%), and high income southern Latin America (1.10%, 0.36% to 2.96%).CONCLUSIONSEighty one per cent of the countries of the world lack information on the epidemiology of psoriasis. The disease occurs more frequently in adults than in children. Psoriasis is unequally distributed across geographical regions; it is more frequent in high income countries and in regions with older populations. The estimates provided can help guide countries and the international community when making public health decisions on the appropriate management of psoriasis and assessing its natural history over time.