Development and first validation of the COPD Assessment Test
Development and first validation of the COPD Assessment Test
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DOI：
10.1183/09031936.00102509
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发表时间：
2009-09-01
影响因子：
24.3
通讯作者：
Leidy, N. Kline
中科院分区：
文献类型：
--
作者：
Jones, P. W.;Harding, G.;Leidy, N. Kline
需要一种有效的、简短的工具来量化慢性阻塞性肺疾病（COPD）在常规实践中的影响，以帮助健康状况评估和患者与医生之间的沟通。目前与健康相关的生活质量问卷提供了COPD的有效评估，但其复杂性限制了常规使用。本研究的目的是开发一个简短的有效的患者完成问卷，COPD评估测试（CAT），评估COPD对健康状况的影响。在三项前瞻性国际研究（欧洲和美国，n=1,503）中，通过COPD患者定性研究确定了21个候选项目。心理测量和拉希分析确定了八个项目适合一个单维模型来形成CAT。对不同国家之间的功能差异进行了测试。内部一致性极好：Cronbach’s alpha=0.88。病情稳定患者（n=53）的复检结果非常好（组内相关系数0.8）。在来自美国的样本中，与copd特定版本的圣乔治呼吸问卷的相关性为r=0.80。稳定患者（n=229）与加重患者（n=67）之间的差异为40分制中的5个单位(12%
There is need for a validated short, simple instrument to quantify chronic obstructive pulmonary disease (COPD) impact in routine practice to aid health status assessment and communication between patient and physician. Current health-related quality of life questionnaires provide valid assessment of COPD, but are complex, which limits routine use.The aim of the present study was to develop a short validated patient-completed questionnaire, the COPD Assessment Test (CAT), assessing the impact of COPD on health status.21 candidate items identified through qualitative research with COPD patients were used in three prospective international studies (Europe and the USA, n=1,503). Psychometric and Rasch analyses identified eight items fitting a unidimensional model to form the CAT. Items were tested for differential functioning between countries. Internal consistency was excellent: Cronbach's alpha=0.88. Test re-test in stable patients (n=53) was very good (intra-class correlation coefficient 0.8). In the sample from the USA, the correlation with the COPD-specific version of the St George's Respiratory Questionnaire was r=0.80. The difference between stable (n=229) and exacerbation patients (n=67) was five units of the 40-point scale (12%; p