Associations of tobacco use and alcohol drinking with laryngeal and hypopharyngeal cancer risks among men in Karunagappally, Kerala, India -Karunagappally cohort study.
Associations of tobacco use and alcohol drinking with laryngeal and hypopharyngeal cancer risks among men in Karunagappally, Kerala, India -Karunagappally cohort study.
复制标题
印度喀拉拉邦Karunagappally的男性喉咙和咽癌风险的烟草使用和饮酒的关联 - 印度喀拉拉邦 - karunagappally队列研究。
DOI：
10.1371/journal.pone.0073716
复制
发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Koriyama C
中科院分区：
文献类型：
--
作者：
Jayalekshmi PA;Nandakumar A;Akiba S;Gangadharan P;Koriyama C
From among a cohort of 65,553 men aged 30–84 in Karunagappally Taluk, Kerala, India, 52 hypopharyngeal cancer cases and 85 laryngeal cancer cases were identified by the Karunagappally Cancer Registry during the period between 1990 and 2009. We conduct Poisson regression analysis of grouped data, taking into account age and education. This study showed that the incidence rates of cancers of the hypopharynx and the larynx were strongly related to the number of bidis smoked a day (P<0.001 for both hypopharyngeal and laryngeal cancers) and duration of bidi smoking (P=0.009; P<0.001). Laryngeal cancer risk was significantly increased by bidi smoking (P<0.001), cigarette smoking (P=0.013) and regular alcohol use (P=0.005). The present study, the first cohort study to examine the association of hypopharyngeal and laryngeal cancer incidence rates with bidi smoking in South Asia, clearly showed dose–response relationships between those cancer risks and bidi smoking; larger amounts of bidi smoked a day and longer durations of bidi smoking increased the incidence rates of those cancers. Tobacco chewing was found not related to the risk of hypopharynx or larynx cancer.
登录
查看更多内容
影响因子：
3.4
作者：
Nair, MK;Nambi, KSV;Reghuram, KN
通讯作者：
Reghuram, KN
影响因子：
7.7
作者：
Gupta, PC;Pednekar, MS;Sankaranarayanan, R
通讯作者：
Sankaranarayanan, R
影响因子：
6.4
作者：
TUYNS, AJ;ESTEVE, J;ZUBIRI, L
通讯作者：
ZUBIRI, L
影响因子：
6.4
作者：
Sapkota, Amir;Gajalakshmi, Vendhan;Boffetta, Paolo
通讯作者：
Boffetta, Paolo
影响因子：
2.2
作者：
Nair, Raghu Ram K.;Rajan, Balakrishnan;Sugahara, Tsutomu
通讯作者：
Sugahara, Tsutomu