Psychometric Validity of the Strengths and Difficulties Questionnaire-Dysregulation Profile
Psychometric Validity of the Strengths and Difficulties Questionnaire-Dysregulation Profile
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DOI：
10.1159/000318164
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发表时间：
2011-01-01
期刊：
影响因子：
3.6
通讯作者：
Roessner, Veit
中科院分区：
文献类型：
--
作者：
Holtmann, Martin;Becker, Andreas;Roessner, Veit
背景资料：在许多严重精神障碍的儿童，临床表现是复杂的共病情感和行为失调。最近，一个高度遗传的行为表型的同时异常的nanobiliary/抑郁，注意力问题，和攻击行为综合征量表已被确定的儿童行为检查表失调概况（CBCL-DP）。本试点研究的目的是使用优势和困难问卷（SDQ）确定与CBCL-DP的等效性。取样和方法：我们采用逐步线性判别分析和受试者工作特征（ROC）分析的数据，从543个连续提到的儿童和青少年，年龄在5-17岁。CBCL和SDQ由父母完成，作为诊断常规的一部分。ICD-10出院诊断在共识会议上确定。结果如下：五个SDQ项目（SDQ-失调特征，SDQ-DP）的组合产生了对有和没有CBCL-DP的儿童的最佳区分，并正确分类了81.0%的受试者，导致曲线下面积为0.93。SDQ-DP的五个项目的内容很好地反映了CBCL-DP捕获的焦虑抑郁，攻击和注意力问题的混合行为表型。SDQ-DP状态与CBCL-DP状态高度相关，最佳定义为SDQ-DP评分>= 5。结论：SDQ-DP的心理测量学特性已经得到了稳健的测试和验证。基于这些结果，临床医生可以使用SDQ-DP作为一个有用的和经济的筛查措施，以改善儿童和青少年严重失调的评估，预防和治疗。未来的研究应该研究这种行为表型的纵向稳定性、遗传力和遗传关联。版权所有（C）2010 S. Karger AG，巴塞尔
Background: In many severely mentally disordered children, the clinical presentation is complicated by comorbid affective and behavioral dysregulation. Recently, a highly heritable behavioral phenotype of simultaneous deviance on the nanxious/depressed, attention problems, and aggressive behavior syndrome scales has been identified on the Child Behavior Checklist Dysregulation Profile (CBCL-DP). The aim of the present pilot study was to determine an equivalent to the CBCL-DP using the Strengths and Difficulties Questionnaire (SDQ). Sampling and Methods: We applied stepwise linear discriminant analyses and receiver operating characteristic (ROC) analysis to data from 543 consecutively referred children and adolescents, aged 5-17 years. The CBCL and the SDQ were completed by parents as part of the diagnostic routine. ICD-10 discharge diagnoses were established in consensus conferences. Results: A combination of five SDQ items (SDQ-Dysregulation Profile, SDQ-DP) yielded the best discrimination of children with and without CBCL-DP and classified 81.0% of the subjects correctly leading to an area under the curve of 0.93. The content of the five SDQ-DP items mirrors well the mixed behavioral phenotype of anxious-depressive, aggressive and attention problems captured by the CBCL-DP. SDQ-DP status was highly correlated with CBCL-DP status and was best defined by a SDQ-DP score >= 5. Conclusions: The psychometric properties of the SDQ-DP have been robustly tested and validated. Based on these results, clinicians may use the SDQ-DP as a useful and economical screening measure to improve the assessment, prevention, and treatment of severe dysregulation in childhood and adolescence. Future investigations should study the longitudinal stability, heritability, and genetic associations of this behavioral phenotype. Copyright (C) 2010 S. Karger AG, Basel