Effects of Titanium Mesh Cage End Structures on the Compressive Load at the Endplate Interface: A Cadaveric Biomechanical Study.
Effects of Titanium Mesh Cage End Structures on the Compressive Load at the Endplate Interface: A Cadaveric Biomechanical Study.
复制标题
钛网笼端部结构对端板界面压缩载荷的影响：尸体生物力学研究
DOI：
10.12659/msm.905466
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发表时间：
2017-06-12
期刊：
影响因子：
--
通讯作者：
He X
中科院分区：
文献类型：
--
作者：
Lu T;Liang H;Liu C;Guo S;Zhang T;Yang B;He X
背景本研究旨在评价在颈椎前路椎体次全切除融合术（ACCF）中，倾斜角度和环形钛网融合器（TMC）末端结构是否可以改善终板界面的压缩载荷。材料/方法23名志愿者接受颈椎侧位X线检查。测量上级终板的倾斜角度，并以此构建TMC端的倾斜度。取新鲜尸体椎体42个，随机分为4个TMC组。记录骨密度、前后径和横径等基线指标。进行单轴压缩测试时，以12°角放置上级终板。评估了四种TMC的最大载荷。结果各组基线指标差异无统计学意义。传统TMC的最大载荷最低（1362.3±221.78 N，p<0.05），而带斜端环的TMC的最大载荷最高（2095.82±285.64 N，p<0.05）。倾斜足印和平端环的最大载荷分别为1806.91±246.98 N和1725.3±213.33 N，显著高于常规足印（p<0.05），但显著低于倾斜端环的最大载荷（p<0.05）。结论TMC端部的环形和倾斜角度均有助于增加压缩力，建议在ACCF中优化TMC结构，以减少TMC下沉的发生率。
Background This study aimed to evaluate whether obliquely angled and ring-shaped titanium mesh cage (TMC) end structures can improve the compressive load on the endplate interface in anterior cervical corpectomy and fusion (ACCF). Material/Methods A total of 23 volunteers underwent cervical lateral x-ray. The oblique angle of the superior endplate was measured, which was used to construct the gradient of the TMC end. Forty-two fresh cadaveric vertebral bodies were harvested and randomly distributed among four TMC groups with different ends. The baseline indicators of bone mineral density and anteroposterior and transverse dimensions were recorded. The superior endplate was placed at an angle of 12° when performing uniaxial compression testing. The maximum loads of the four TMCs were assessed. Results There were no significant differences among the groups regarding the baseline indicators. The conventional TMC had the lowest maximum load (1362.3±221.78 N, p<0.05), whereas the TMC with an obliquely end ring had the highest maximum load (2095.82±285.64 N, p<0.05). The maximum loads of the TMCs with oblique footprints and flat end ring were much higher than that of the conventional TMC (p<0.05) but significantly lower than that of the TMC with the obliquely end ring (p<0.05), with average values of 1806.91±246.98 N and 1725.3±213.33 N, respectively. Conclusions Both the ring shape and oblique angle of the TMC end contributed to an increase in compressive force and are advocated for use in TMC structure optimization to decrease the incidence of TMC subsidence in ACCF.