Alcohol and memory: amnesia and short-term memory function during experimentally induced intoxication.
Alcohol and memory: amnesia and short-term memory function during experimentally induced intoxication.
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酒精和记忆：实验诱导中毒期间的健忘症和短期记忆功能。
DOI：
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发表时间：
1971
影响因子：
17.7
通讯作者：
J. Mendelson
中科院分区：
文献类型：
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作者：
J. Tamerin;S. Weiner;R. Poppen;P. Steinglass;J. Mendelson
这项研究是第一次尝试检查酒精在持续的实验性醉酒期间的昏迷。13名有昏迷病史的男性酗酒者连续12至14天大量饮酒。每天进行短期记忆和24小时回忆的评估。随着醉酒程度的增加，短期记忆受到明显的进行性损害。24小时回忆障碍也与前一天的醉酒程度有关。出现了停电，特别是在短期记忆功能受损的受试者中。相反，短期记忆完好无损的受试者有正常的24小时回忆。
This study represents the first attempt to examine the alcoholic blackout during a sustained period of experimental intoxication. Thirteen male alcoholics with histories of blackouts drank large amounts of beverage alcohol for 12 to 14 days. Daily assessments of short-term memory and 24-hour recall were made. Short-term memory was significantly and progressively impaired with increasing levels of intoxication. Impairment of 24-hour recall was also related to level of intoxication on the preceding day. Blackouts occurred, particularly among subjects with impaired short-term memory function. Conversely, subjects with intact short-term memory had normal 24-hour recall.