PROSPECTIVE-STUDY OF THE FREQUENCY AND SIZE DISTRIBUTION OF POLYPS MISSED BY COLONOSCOPY
PROSPECTIVE-STUDY OF THE FREQUENCY AND SIZE DISTRIBUTION OF POLYPS MISSED BY COLONOSCOPY
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DOI：
10.1093/jnci/82.22.1769
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发表时间：
1990-11-21
影响因子：
10.3
通讯作者：
GAREWAL, H
中科院分区：
文献类型：
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作者：
HIXSON, LJ;FENNERTY, MB;GAREWAL, H
解释结直肠息肉化学预防试验结果的一个重要决定因素是结肠镜检查中息肉的漏诊率。我们前瞻性地对90名患者进行了由两名交替检查者进行的串联结肠镜检查。在69例（76.7%）患者中，组织学记录了221处肿瘤病变。在31名患者中检测到的总共58个病变中，没有尺寸大于或等于10 mm的肿瘤病变被遗漏; 16%的小型（≤ 10 mm）肿瘤病变被遗漏。第一次检查者漏诊了12.3%的中等大小（6 - 9 mm）的肿瘤性息肉。我们的结论是，一个有经验的结肠镜医师将错过约15%的结直肠肿瘤性息肉小于10毫米的大小在设置充分的肠道准备。大（≥10 mm）息肉很少被遗漏，然而，在我们的研究中，"遗漏"率等于0，95%置信限为4.64%。
An important determinant in interpreting the results of colorectal polyp chemoprevention trials is the rate of polyps missed during colonoscopic examination. We prospectively examined 90 patients by tandem colonoscopy performed by two alternating examiners. In 69 (76.7%) patients, 221 neoplastic lesions were documented histologically. Of a total of 58 lesions detected in 31 patients, no neoplastic lesion greater than or equal to 10 mm in size was missed; 16% of diminutive (.ltoreq. 5 mm) neoplastic polyps and 12.3% of medium-sized (6-9 mm) neoplastic polyps were missed by the first examiner. We conclude that an experienced colonoscopist will miss about 15% of colorectal neoplastic polyps less than 10 mm in size in the setting of adequate bowel preparation. Large (.gtoreq. 10 mm) polyps were rarely missed, however, with the "miss" rate in our study equal to 0, with a 95% confidence limit of 4.64%.