Selective Excitation of Concomitant Electrochemiluminophores: Tuning Emission Color by Electrode Potential
Selective Excitation of Concomitant Electrochemiluminophores: Tuning Emission Color by Electrode Potential
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DOI：
10.1002/anie.201200814
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发表时间：
2012-01-01
影响因子：
16.6
通讯作者：
Francis, Paul S.
中科院分区：
文献类型：
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作者：
Doeven, Egan H.;Zammit, Elizabeth M.;Francis, Paul S.
三(2，2о联吡啶)Ru(II)([Ru(Bpy)3]2+)离子与共反应物在水溶液中的电致化学发光是一种非常灵敏和通用的检测系统[2]，目前在世界各地的商业仪器中被用于快速筛选和量化临床生物标志物、食源性病原体和生物制剂。[3][Ru(Bpy)3]2+及其相关络合物的电致化学发光在发光设备、[4]阴离子传感、[5]多路(微阵列)免疫分析等领域继续出现。[6]检测受损或特定序列的DNA，[7]和分子编码-解码。[8]对支持这种应用的高级ECL试剂和策略的追求仍然很密集，[2f，h]，并受到试剂性能(例如ECL效率、溶解度、光谱分布)的操作进展的推动，这些进展源于对Ru、Ir和其他金属络合物的广泛研究，[9]和纳米技术的创新。
The electrogenerated chemiluminescence (ECL) of tris (2, 2оbipyridine) ruthenium (II)([Ru (bpy) 3] 2+) ions with co-reactants in aqueous solution [1] is a remarkably sensitive and versatile detection system [2] that is now exploited in commercial instrumentation throughout the world for rapid screening and quantification of clinical biomarkers, food borne pathogens and biowarfare agents.[3] New applications of the ECL of [Ru (bpy) 3] 2+ and related complexes continue to appear in areas as diverse as light-emitting devices,[4] anion sensing,[5] multiplexed (microarray) immunoassays,[6] detection of damaged or sequence-specific DNA,[7] and molecular encoding–decoding.[8]The pursuit of superior ECL reagents and strategies that underpin such applications remains intensive,[2f, h] and is spurred by advances in the manipulation of reagent properties (for example ECL efficiency, solubility, spectral distribution) derived from extensive investigation of ruthenium, iridium, and other metal complexes,[9] and innovations in nanotechnology.[10]