The Use of Exparel (Liposomal Bupivacaine) to Manage Postoperative Pain in Unilateral Total Knee Arthroplasty Patients
The Use of Exparel (Liposomal Bupivacaine) to Manage Postoperative Pain in Unilateral Total Knee Arthroplasty Patients
复制标题
DOI：
10.1016/j.arth.2014.09.004
复制
发表时间：
2015-02-01
影响因子：
3.5
通讯作者：
Arce, Britney R.
中科院分区：
文献类型：
--
作者：
Surdam, Jonathan W.;Licini, David J.;Arce, Britney R.
为了加速康复，我们继续努力改善全膝关节置换术（TKA）后的疼痛。本研究的目的是评估全膝关节置换术后的疼痛控制。对 80 名连续患者进行了一项随机前瞻性研究，比较 Exparel 与股神经阻滞 (FNB)。住院患者疼痛控制是主要结果。次要结果指标包括 ROM（伸展和屈曲）、恶心和呕吐、麻醉剂消耗、行走距离和住院时间 (LOS)。各组之间在疼痛、恶心和呕吐以及麻醉品消耗方面没有统计学上的显着差异。 FNB 组具有更大的屈曲能力，但 Exparel 组改善了早期下床活动并降低了 LOS。 Exparel 在 TKA 后提供了与 FNB 类似的疼痛缓解效果，且不影响早期康复。 (C) 2014 Elsevier Inc. 保留所有权利。
Efforts continue to improve pain after total knee arthroplasty (TKA) in order to allow for accelerated rehabilitation. The purpose of this study was to evaluate pain control after TKA. A randomized prospective study of 80 consecutive patients was performed comparing Exparel versus femoral nerve block (FNB). Inpatient pain control was the primary outcome. Secondary outcome measures included ROM (extension and flexion), nausea and vomiting, narcotic consumption, ambulation distance, and length of stay (LOS). There were no statistically significant differences between the groups with regard to pain, nausea and vomiting, and narcotic consumption. The FNB group had greater flexion but the Exparel group had improved early ambulation and decreased LOS. Exparel provided similar pain relief to a FNB after TKA without compromising early rehabilitation. (C) 2014 Elsevier Inc. All rights reserved.