MEDICATION ADHERENCE PATTERNS IN CHRONIC OBSTRUCTIVE PULMONARY-DISEASE
MEDICATION ADHERENCE PATTERNS IN CHRONIC OBSTRUCTIVE PULMONARY-DISEASE
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DOI：
10.1378/chest.99.4.837
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发表时间：
1991-04-01
期刊：
影响因子：
9.6
通讯作者：
BAILEY, WC
中科院分区：
文献类型：
--
作者：
DOLCE, JJ;CRISP, C;BAILEY, WC
虽然COPD的医学治疗已经取得了进展，但未能坚持药物治疗方案对有效管理构成了重大障碍。此外，没有关于美国境内患者依从性的数据。这项调查的数据表明，来自美国东南部地区一家医疗中心的78名门诊患者平均处方了6.26种药物，这些药物具有不同的给药方案和不同的给药模式。依从性较差，42例患者（54%）未充分使用药物，39例患者（50%）在呼吸窘迫期间过度使用药物，24例患者（31%）使用无效的吸入器给药技术。处方模式和依从性与人口统计学变量无关;然而，依从性与药物类别和情境变量相关。
While medical treatment of COPD has advanced, the failure to adhere to regimens for medication poses a significant barrier to effective management. Furthermore, no data are available regarding adherence for patients within the United States. Data from this investigation indicate that 78 outpatients from a medical center in the southeastern region of the United States were prescribed an average of 6.26 medications with both various dosing schedules and different modes of administration. Adherence was poor, with 42 patients (54 percent) underutilizing medications, 39 patients (50 percent) overutilizing medications during periods of respiratory distress, and 24 patients (31 percent) employing ineffective inhaler dosing techniques. Prescription patterns and adherence were not associated with demographic variables; however, adherence was related to classes of medication and situational variables.