A Defect in Zinc Finger Protein Double B-box 1a (DBB1a) Causes Abnormal Floral Development in Arabidopsis
A Defect in Zinc Finger Protein Double B-box 1a (DBB1a) Causes Abnormal Floral Development in Arabidopsis
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DOI：
10.1007/s12374-009-9070-6
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发表时间：
2009-09
影响因子：
2.9
通讯作者：
Qiming Wang;Xiaoju Tu;Keqin Deng;Jianxin Zeng;Xiaoying Zhao;Dong-Ying Tang;Xuanming Liu
中科院分区：
文献类型：
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作者：
Qiming Wang;Xiaoju Tu;Keqin Deng;Jianxin Zeng;Xiaoying Zhao;Dong-Ying Tang;Xuanming Liu
到目前为止，双B盒(DBB)型锌指蛋白已被证明与拟南芥的光形态发生有关。在这里，我们证明了DBB1aa在胚胎、细胞和花中表达。在突变植株中，DBB1的错误表达导致花器官的数量和模式异常。我们进一步证明，DBB1可以调节几个花同源异型基因的表达，包括APETALA 2、APETALA 3、雌蕊和AGAMOUS。有趣的是，参与器官边界建立的microRNA基因MiR172的表达在dbb1突变植物中也受到错误调控。我们的研究发现，DDB1在调控花同源异型基因和miR172的表达方面发挥了以前未知的作用，这对于理解花模式的形成是重要的。
The double B-box (DBB) type zinc finger protein has thus far been shown to be involved in photomorphegenesis inArabidopsis thaliana. Here, we show thatDBB1ais expressed in the embryo, cytolden, and flower. Misexpression ofDBB1ain mutant plants resulted in abnormal numbers and patterns of floral organs. We further show thatDBB1acould regulate expression of several floral homeotic genes, includingAPETALA 2,APETALA 3,PISTILLATA, andAGAMOUS. Interestingly, expression of the microRNA geneMiR172, which is involved in organ boundary establishment, was also misregulated in thedbb1amutant plants. Our study identified a previously uncharacterized role ofDDB1ain regulation of expression of floral homeotic genes andmiR172, which is important for understanding of floral pattern formation.