Computing graphlet signatures of network nodes and motifs in Cytoscape with GraphletCounter

Computing graphlet signatures of network nodes and motifs in Cytoscape with GraphletCounter
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DOI:
10.1093/bioinformatics/btr637
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发表时间:
2012-01-15
期刊:
影响因子:
5.8
通讯作者:
Soenmez, Kemal
Soenmez, Kemal
中科院分区:
生物学3区
文献类型:
--
作者:
Whelan, Christopher;Soenmez, Kemal

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Biological network analysis can be enhanced by examining the connections between nodes and the rest of the network. For this purpose we have developed GraphletCounter, an open-source software tool for computing graphlet degree signatures that can operate on its own or as a plug- in to the network analysis environment Cytoscape. A unique characteristic of GraphletCounter is its ability to compute the graphlet signatures of network motifs, which can be specified by files generated by the motif-finding tool mfinder. GraphletCounter displays graphlet signatures for visual inspection within Cytoscape, and can output graphlet data for integration with larger workflows.