Infantile Choroid Plexus Papilloma with Multiple Peritumoral Cysts
Infantile Choroid Plexus Papilloma with Multiple Peritumoral Cysts
复制标题
婴儿脉络丛乳头状瘤伴多发性瘤周囊肿
DOI：
10.1016/j.wneu.2022.03.068
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发表时间：
2022
影响因子：
2
通讯作者：
Takeshima Hideo
中科院分区：
文献类型：
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作者：
Horinouchi Shoichi;Watanabe Takashi;Takeshima Hideo
婴儿脉络丛乳头状瘤（CPP）合并多发性瘤周囊肿是CPP的一种罕见变异，临床过程和最佳治疗方法在很大程度上是未知的。一个9个月大的男孩在左侧脑室出现一个大的实体瘤，伴有多发性瘤周囊肿、蛛网膜囊肿和脑积水，其中含有高蛋白含量的黄色素液。这些囊肿的收缩和解决脑积水后实现全切除肿瘤的富血管实性部分。组织学检查证实肿瘤的实性部分为CPP，并显示瘤周囊肿壁由反应性胶质增生组成，无肿瘤细胞。术后12个月的随访磁共振成像显示这些囊肿保持稳定。无强化瘤周囊肿的CPP可以通过仅切除肿瘤的实性部分而无需永久性脑脊液分流来治疗。
Infantile choroid plexus papilloma (CPP) associated with multiple peritumoral cysts is a rare variant of CPP, and clinical course and optimal management are largely unknown. A 9-month-old boy presented with a large solid tumor in the left lateral ventricle associated with multiple peritumoral cysts, arachnoid cysts, and hydrocephalus containing xanthochromic fluid with high protein content. Shrinkage of these cysts and resolution of hydrocephalus were achieved after total resection of the hypervascular solid part of the tumor. Histological examination confirmed the solid part of the tumor as CPP and showed that the wall of the peritumoral cysts consisted of reactive gliosis without neoplastic cells. Follow-up magnetic resonance imaging 12 months after surgery revealed that these cysts remained stable. CPP with nonenhancing peritumoral cysts can be managed by resection of only the solid part of the tumor without permanent cerebrospinal fluid diversion.