Cardiovascular Health Is Associated With Disability Among Older Community Dwelling Men and Women
Cardiovascular Health Is Associated With Disability Among Older Community Dwelling Men and Women
复制标题
DOI：
10.1177/0898264318778417
复制
发表时间：
2019-09-01
影响因子：
2.8
通讯作者：
Talegawkar, Sameera A.
中科院分区：
文献类型：
--
作者：
Jin, Yichen;Tanaka, Toshiko;Talegawkar, Sameera A.
目的：本研究的目的是调查整体心血管健康（CVH）指数是否与老年人的残疾相关。方法：使用了 InCHIANTI 研究（基安蒂的 Invecchiare，基安蒂地区老龄化，≥ 65 岁，55% 女性）的 925 名参与者的数据，中位随访时间为 9 年。 CVH 评分通过吸烟状况、体力活动、体重指数、饮食质量、血压、血浆胆固醇和空腹血糖进行评估。使用日常生活工具性活动（IADL 残疾>0 与0）和日常生活活动（ADL 残疾>0 与0）来检查残疾。广义估计方程和 Cox 模型评估了 9 年内基线 CVH 与残疾和恶化之间的关系。结果：CVH 评分每增加 1 分，ADL (p < .001) 和 IADL (p < .001) 残疾几率降低 23% 和 17%，并且可以防止 9 年内残疾恶化。 Cox 模型证明，CVH 评分每增加 1 分与 ADL（风险比 [HR] = 0.86，p = .005）和 IADL（HR = 0.91，p = .007）残疾风险降低相关。讨论：在老年人中，更好的 CVH 与较低的残疾风险和 9 年内恶化的风险相关。
Objective: The aim of this study was to investigate whether an index of overall cardiovascular health (CVH) is associated with disability in older individuals. Method: Data on 925 participants of the InCHIANTI study (Invecchiare in Chianti, aging in the Chianti area, >= 65 years, 55% women) with median follow-up of 9 years were used. CVH score was assessed by smoking status, physical activity, body mass index, diet quality, blood pressure, plasma cholesterol, and fasting blood glucose. Disability was examined using instrumental activities of daily living (IADL disabilities >0 vs. 0) and activities of daily living (ADL disabilities >0 vs. 0). Generalized estimating equations and Cox models assessed relationships between baseline CVH with disability and worsening over 9 years. Results: A 1-point increase in the CVH score was associated with 23% and 17% of lower odds of ADL (p < .001) and IADL (p < .001) disability and was protective of worsening of disability over 9 years. Cox models demonstrated that a 1-point increase in CVH score was associated with lower hazards of both ADL (hazard ratio [HR] = 0.86, p = .005) and IADL (HR = 0.91, p = .007) disability. Discussion: Among older individuals, better CVH was associated with lower risk of disability and worsening over 9 years.