Epidemiologic features of Kawasaki disease in Japan: results from the nationwide survey in 2005-2006.

Epidemiologic features of Kawasaki disease in Japan: results from the nationwide survey in 2005-2006.
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DOI:
10.2188/jea.je2008001
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发表时间:
2008
影响因子:
4.7
通讯作者:
Yanagawa H
Yanagawa H
中科院分区:
医学3区
文献类型:
--
作者:
Nakamura Y;Yashiro M;Uehara R;Oki I;Watanabe M;Yanagawa H

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川崎病的最新流行病学特征尚不清楚。2007年进行了第19次全国疾病调查,目标是2005年和2006年受该病影响的患者。所有100张及以上床位医院的儿科及儿科医院在2年调查期间报告所有川崎病患者。1543个部门和医院共报告了20475名患者(2005年10041名,2006年10434名)。男性11892例,女性8583例。年平均发病率为每10万名0-4岁儿童184.6例。在过去的12年中,患者数量和发病率显著增加。年龄特异性发病率呈单峰分布,6-8月龄为高峰。急性期心脏病变和心脏后遗症的发生率在婴幼儿和老年患者中较高。日本的川崎病患者数量和发病率不断增加。
The most recent epidemiologic features of Kawasaki disease are unknown. The 19th nationwide survey of the disease was conducted in 2007, targeting patients who were affected by this disease in 2005 and 2006. All pediatric departments in hospitals with 100 or more beds and pediatric hospitals were asked to report all Kawasaki disease patients during the 2 survey years. From 1543 departments and hospitals, a total of 20475 patients (10041 in 2005 and 10434 in 2006) were reported. There were 11892 male patients and 8583 female patients. The average annual incidence rate was 184.6 per 100000 children aged 0-4 years. The number of patients and the incidence rate have increased significantly during the past 12 years. The age-specific incidence rate was distributed monomodally with a peak at 6-8 months of age. The prevalence of cardiac lesions in the acute phase of the disease and of cardiac sequelae were higher among infants and old patients. The number of patients with Kawasaki disease and its incidence rate in Japan are continuously increasing.