Temporal lobe surface area measurements on MRI in normal and dyslexic readers.
Temporal lobe surface area measurements on MRI in normal and dyslexic readers.
复制标题
正常和阅读困难读者的 MRI 颞叶表面积测量。
DOI：
10.1016/0028-3932(93)90130-r
复制
发表时间：
1993
期刊：
影响因子：
2.6
通讯作者：
Duara,R
中科院分区：
文献类型：
--
作者：
Kushch,A;Gross-Glenn,K;Jallad,B;Lubs,H;Rabin,M;Feldman,E;Duara,R
在阅读障碍的神经解剖学研究中，对17名阅读障碍患者和21名非阅读障碍患者的颞叶上级表面（SSTL）进行了MRI扫描测量。非阅读障碍者的SSTL区的前半部分和后半部分均表现出显著的对称性，而阅读障碍者的SSTL区则表现出对称性。总的SSTL面积显示出更大的非阅读障碍者比阅读障碍者的不对称性。阅读障碍者的Woodcock-Johnson通道理解得分与SSTL后部不对称性之间存在显著相关（r= 0.69，P = 0.005），得分越高，SSTL后部不对称性越大。这表明在阅读障碍者中，SSTL不对称的方向可能是阅读理解问题严重程度的危险因素和/或标志。
In a neuroanatomical study of dyslexia, measurements were made of the superior surface of the temporal lobe (SSTL) on MRI scans in a sample of 17 dyslexics and 21 non-dyslexic subjects. Both anterior and posterior halves of the SSTL area showed significant leftward asymmetry in non-dyslexics, but showed symmetry in dyslexics. The total SSTL area showed greater leftward asymmetry in non-dyslexics than in dyslexics. The dyslexics also revealed a significant correlation (r= 0.69,P= 0.005) between Woodcock-Johnson Passage Comprehension scores and posterior SSTL asymmetry, such that those with higher scores had more leftward asymmetry. This suggests that among dyslexics the direction of SSTL asymmetry may serve as a risk factor and/or a marker for the severity of reading comprehension problems.