Optimal detection pinhole for lowering speckle noise while maintaining adequate optical sectioning in confocal reflectance microscopes
Optimal detection pinhole for lowering speckle noise while maintaining adequate optical sectioning in confocal reflectance microscopes
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DOI：
10.1117/1.jbo.17.8.085001
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发表时间：
2012-08-01
影响因子：
3.5
通讯作者：
Rajadhyaksha, Milind
中科院分区：
文献类型：
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作者：
Glazowski, Christopher;Rajadhyaksha, Milind
当使用窄谱线宽度和单空间模式照明时，相干散斑影响所得到的图像，尽管这些是提供最佳辐射成本比的相同光源特性。然而，可以选择检测针孔的合适尺寸以保持足够的光学切片，同时使散斑噪声的概率密度更正常并降低其影响。其结果是质量更好的图像与改善的对比度，这是更容易阅读。理论统计和实验结果表明，检测针孔的大小是一个基本参数，设计用于混浊介质的成像系统。(C)2012年，美国光电仪器工程师学会（SPIE）。[DOI：10.1117/1.JBO.17.8.085001]
Coherent speckle influences the resulting image when narrow spectral line-width and single spatial mode illumination are used, though these are the same light-source properties that provide the best radiance-to-cost ratio. However, a suitable size of the detection pinhole can be chosen to maintain adequate optical sectioning while making the probability density of the speckle noise more normal and reducing its effect. The result is a qualitatively better image with improved contrast, which is easier to read. With theoretical statistics and experimental results, we show that the detection pinhole size is a fundamental parameter for designing imaging systems for use in turbid media. (C) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.8.085001]