EAE: An immunologist's magic eye

EAE: An immunologist's magic eye
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DOI:
10.1002/eji.200939568
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发表时间:
2009-08-01
影响因子:
5.4
通讯作者:
Wekerle, Hartmut
Wekerle, Hartmut
中科院分区:
医学3区
文献类型:
--
作者:
Krishnamoorthy, Gurumoorthy;Wekerle, Hartmut

文献摘要

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EAE有许多形状和颜色。EAE的个体变体在临床、免疫学和结构上呈现出令人困惑的不同方面和特征的复杂性。但是,在这个看似混乱的图像中,受过教育的眼睛将识别出追溯免疫反应基本特征的模式,特别是自身免疫和自我耐受。因此,EAE及其变体可以比作自动立体图,即它们是免疫学家的魔眼。
EAE comes in many shapes and colors. Individual variants of EAE present a baffling complexity of different aspects and traits, clinical, immunological, and structural. But, embedded in this seemingly chaotic image, the educated eye will discern patterns that retrace fundamental features of immune response, in particular, autoimmunity and self-tolerance. EAE and its variants thus can be likened to an auto-stereogram, i.e. they are an immunologist's magic eye.