Heritability of aggression and irritability: A twin study of the Buss-Durkee aggression scales in adult male subjects
Heritability of aggression and irritability: A twin study of the Buss-Durkee aggression scales in adult male subjects
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DOI：
10.1016/s0006-3223(96)00257-0
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发表时间：
1997-02-01
影响因子：
10.6
通讯作者：
Seroczynski, AD
中科院分区：
文献类型：
--
作者：
Coccaro, EF;Bergeman, CS;Seroczynski, AD
为了确定遗传和环境对男性受试者攻击性和易怒性评估的影响程度，巴斯-德基敌意量表 (BDHI) 的“运动攻击性”子量表被邮寄给越南时代双胞胎登记处的 1208 名男性双胞胎。来自 182 和 118 个异卵双胞胎的数据是可用的，并使用模型拟合程序进行了分析。四个 BDHI 子量表中的三个显示出显着的非累加性遗传力：间接攻击为 40%，易怒为 37%，言语攻击为 28%。加性遗传方差占直接攻击个体差异的 47%。非共享但不共享的环境影响有助于解释模型中的差异，估计范围从 53%（直接攻击）到 72%（言语攻击）。由于其中一些 BDHI 量表已被证明与中枢血清素功能指数相关，因此这些量表所反映的冲动攻击性可能在男性中具有遗传性。 (C) 1997 年生物精神病学协会。
To determine the degree of genetic and environmental influences on assessments of aggression and irritability in male subjects, the ''Motor Aggression'' subscales of the Buss-Durkee Hostility Inventory (BDHI) were mailed to 1208 male twins in the Vietnam Era Twin Registry. Data from monozygotic 182 and 118 dizygotic twin pairs were available and were analyzed using model-fitting procedures. Three of the four BDHI subscales demonstrated significant heritability of a nonadditive nature: 40% for Indirect Assault, 37% for Irritability, and 28% for Verbal Assault. Additive genetic variance accounted for 47% of the individual differences in Direct Assault. Nonshared, but not shared, environmental influences contributed to explaining the variance in the model, with estimates ranging from 53% (Direct Assault) to 72% (Verbal Assault), Because some of these BDHI scales have been shown to correlate with indices of central serotonin function, it is possible that impulsive aggression, as reflected by these scales, is heritable in men. (C) 1997 Society of Biological Psychiatry.