The significance of quality for efficacy and safety of herbal medicinal products
The significance of quality for efficacy and safety of herbal medicinal products
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DOI：
10.1177/009286150003400102
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发表时间：
2000-01-01
影响因子：
--
通讯作者：
Busse, W
中科院分区：
文献类型：
--
作者：
Busse, W
任何药物产品的功效和安全性都是由其所含的化合物（所需和不需）决定的。质量控制的目的是确保制剂的每个剂量释放相同量的活性成分，并尽可能不含杂质。由于草药产品是源自生物来源的复杂混合物，因此需要做出巨大努力来保证恒定和足够的质量。通过仔细选择植物材料和标准化的生产工艺，草药产品成分的模式和浓度应尽可能保持恒定，因为这是可重现治疗结果的先决条件。随着草药产品的使用越来越多，特别是在美国，未来全球草药产品的标签实践应充分解决质量问题。
The efficacy and safety of any pharmaceutical product is determined by the compounds (desired and undesired) which if contains. The purpose of quality control is to ensure that each dosage Emit of the drug product delivers the same amount of active ingredients and is, as far as possible, free of impurities. As herbal medicinal products are complex mixtures which originate from biological sources, great efforts are necessary to guarantee a constant and adequate quality. By carefully selecting the plant material and a standardized manufacturing process the pattern and concentration of constituents of herbal medicinal products should be kept as constant as possible as this is a prerequisite for reproducible therapeutic results. With the increasing use of herbal products, particularly in the United States, the future worldwide labeling practice for herbal products should adequately address quality aspects.