The effect of low-intensity pulsed ultrasound on the osseointegration of titanium dental implants
The effect of low-intensity pulsed ultrasound on the osseointegration of titanium dental implants
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DOI：
10.1016/j.bjoms.2011.03.001
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发表时间：
2012-04-01
影响因子：
1.8
通讯作者：
Ding, Yuxiang
中科院分区：
文献类型：
--
作者：
Liu, Qing;Liu, Xin;Ding, Yuxiang
我们的目的是记录低强度脉冲超声（LIPUS）对10只新西兰兔骨内牙种植体骨整合的影响。将一个带螺钉的钛植入物插入每只家兔膝关节股骨和胫骨的干骺端区域，共40个植入物。用LIPUS照射一侧膝关节外侧区域，包括植入物，每天两次，每次10分钟，持续21天。另一侧作为对照，给予“假”照射。照射后0、2、4、6、8周各处死2只家兔。显微计算机断层扫描（mu CT）、组织学检查和种植体拔出试验用于判断骨对钛种植体的反应。组织学和mu CT检查表明，LIPUS治疗侧的种植体骨整合发生得更早，更有效地比对照侧。力学测试表明，LIPUS治疗侧种植体的最大轴向拔出强度大于对照侧。我们的结论是，LIPUS有可能加速牙种植体的骨整合。(C)2011年英国口腔颌面外科医师协会。由爱思唯尔有限公司出版。保留所有权利。
Our aim was to record the effect of low-intensity pulsed ultrasound (LIPUS) on the osseointegration of endosseous dental implants in 10 New Zealand rabbits. One titanium implant with screw was inserted into the metaphyseal region of each femur and tibia in the knee joints of each rabbit, making a total of 40 implants. The area of one lateral knee joint, including implants, was irradiated with LIPUS for 10 min twice a day for 21 days. The other side acted as control, having been given "sham" irradiation. Two rabbits were killed at each of 0, 2, 4, 6, and 8 weeks after irradiation. A micro-computed tomogram (mu CT), histological examination, and implant pull-out test were used to judge the reactions of the bone to the titanium implant. Histological and mu CT examinations showed that osseointegration of the implants on the LIPUS-treated side happened earlier and more effectively than on the control side. The mechanical test showed that the maximal axial pull-out strength of the implants on the LIPUS-treated side was greater than that on the control side. We conclude that LIPUS has the potential to accelerate the osseointegration of dental implants. (C) 2011 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.