CATALYTIC ASYMMETRIC INDUCTION FROM PROCHIRAL CYCLIC ACID ANHYDRIDES USING CINCHONA ALKALOIDS
CATALYTIC ASYMMETRIC INDUCTION FROM PROCHIRAL CYCLIC ACID ANHYDRIDES USING CINCHONA ALKALOIDS
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DOI：
10.1039/c39850001717
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发表时间：
1985-01-01
影响因子：
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通讯作者：
ODA, J
中科院分区：
文献类型：
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作者：
HIRATAKE, J;YAMAMOTO, Y;ODA, J
催化量的金鸡纳生物碱（2）使前手性环酸酐（1）与甲醇发生不对称开环反应，产物对映体过量高达70%，转化为光学活性内酯。
Asymmetric ring-opening of prochiral cyclic acid anhydrides (1) with methanol was effected by a catalytic amount of cinchona alkaloids (2) with an enantiomeric excess of up to 70% and the product was converted into optically active lactones.