MagNI: A Magnetoelectrically Powered and Controlled Wireless Neurostimulating Implant.
MagNI: A Magnetoelectrically Powered and Controlled Wireless Neurostimulating Implant.
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DOI：
10.1109/tbcas.2020.3037862
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发表时间：
2020-12
影响因子：
5.1
通讯作者：
Yang K
中科院分区：
文献类型：
--
作者：
Yu Z;Chen JC;Alrashdan FT;Avants BW;He Y;Singer A;Robinson JT;Yang K
本文介绍了首款利用磁电 (ME) 效应进行电源和数据传输的无线可编程神经刺激器。由于组织吸收率低、错位敏感性低和功率传输效率高，ME 效应能够以低谐振频率 (~250 kHz) 安全地将高功率水平 (几毫瓦) 传输到体内深处 (30 毫米深度) 的毫米级植入物。所展示的 MagNI（磁电神经植入物）由 1.5 mm2 180 nm CMOS 芯片、内部构建的 4 × 2 mm ME 薄膜、储能电容器以及总体积为 8.2 mm3 的柔性聚酰亚胺基板上的板载电极组成。该芯片功耗为 23.7 μW，在源幅度变化（1V 变化容差）下具有强大的系统控制和数据恢复机制。该系统提供完全可编程的双相电流控制刺激，其模式涵盖 0.05 至 1.5 mA 幅度、64 至 512 μs 脉冲宽度和 0 至 200 Hz 重复频率，用于神经刺激。
This paper presents the first wireless and programmable neural stimulator leveraging magnetoelectric (ME) effects for power and data transfer. Thanks to low tissue absorption, low misalignment sensitivity and high power transfer efficiency, the ME effect enables safe delivery of high power levels (a few milliwatts) at low resonant frequencies (~250 kHz) to mm-sized implants deep inside the body (30-mm depth). The presented MagNI (Magnetoelectric Neural Implant) consists of a 1.5-mm2 180-nm CMOS chip, an in-house built 4 × 2 mm ME film, an energy storage capacitor, and on-board electrodes on a flexible polyimide substrate with a total volume of 8.2 mm3. The chip with a power consumption of 23.7 μW includes robust system control and data recovery mechanisms under source amplitude variations (1-V variation tolerance). The system delivers fully-programmable bi-phasic current-controlled stimulation with patterns covering 0.05-to-1.5-mA amplitude, 64-to-512-μs pulse width and 0-to-200-Hz repetition frequency for neurostimulation.