Ultra-narrow surface lattice resonances in plasmonic metamaterial arrays for biosensing applications
Ultra-narrow surface lattice resonances in plasmonic metamaterial arrays for biosensing applications
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DOI：
10.1016/j.bios.2017.12.001
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发表时间：
2018-05-01
影响因子：
12.6
通讯作者：
Kabashin, Andrei V.
中科院分区：
文献类型：
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作者：
Danilov, Artem;Tselikov, Gleb;Kabashin, Andrei V.
当在金纳米颗粒的周期性超材料晶格（类似于100 nm）上激发时，局部等离子体共振（LPR）可以通过沿阵列平面沿着传播的衍射波耦合，这导致等离子体共振线形的急剧变窄（下至几nm的半峰全宽）和反射光的相位奇异性的产生。这些现象对于等离子体生物传感器的性能的改进看起来非常有希望，但是这种衍射耦合的等离子体共振（也称为等离子体表面晶格共振（PSLR））的实施条件并不总是与意味着将纳米颗粒放置在玻璃基板和样品介质（空气、水）之间的生物感测布置相容。在这里，我们考虑的激发条件和性能的PSLR阵列的玻璃基板支持的单和双Au纳米粒子（类似于100-200 nm），安排在一个周期性的超材料晶格，在直接和衰减全反射（ATR）的几何形状，并评估其灵敏度的变化的折射率（RI）的相邻样品介电介质。首先，我们确定介质（PSLRair，PSLRwat的空气和水，分别）和基板（PSLRsub）模式对应于耦合的个别等离子体激元振荡在介质和基板相关的衍射截止边缘。我们表明，介质模式RI变化的光谱灵敏度是由晶格周期性直接和ATR几何形状（类似于320 nm每RIU变化在我们的情况下），而基板模式表现出低得多的灵敏度。我们还表明，PSLR的相位灵敏度可以超过10（5）度的相移每RIU的变化，从而优于所有其他等离子体传感器对应的相关参数。最后，我们证明了等离子体超材料阵列的表面晶格共振的生物传感使用标准的链霉亲和素-生物素亲和模型的适用性。结合纳米级架构的优点，包括电场的剧烈集中，在纳米级操纵的可能性等，以及高相位和光谱灵敏度，PSLR承诺目前最先进的等离子体生物传感技术的进步，单分子标记的检测。
When excited over a periodic metamaterial lattice of gold nanoparticles (similar to 100 nm), localized plasmon resonances (LPR) can be coupled by a diffraction wave propagating along the array plane, which leads to a drastic narrowing of plasmon resonance lineshapes (down to a few nm full-width-at-half-maximum) and the generation of singularities of phase of reflected light. These phenomena look very promising for the improvement of performance of plasmonic biosensors, but conditions of implementation of such diffractively coupled plasmonic resonances, also referred to as plasmonic surface lattice resonances (PSLR), are not always compatible with biosensing arrangement implying the placement of the nanoparticles between a glass substrate and a sample medium (air, water). Here, we consider conditions of excitation and properties of PSLR over arrays of glass substrate-supported single and double Au nanoparticles (similar to 100-200 nm), arranged in a periodic metamaterial lattice, in direct and Attenuated Total Reflection (ATR) geometries, and assess their sensitivities to variations of refractive index (RI) of the adjacent sample dielectric medium. First, we identify medium (PSLRair, PSLRwat for air and water, respectively) and substrate (PSLRsub) modes corresponding to the coupling of individual plasmon oscillations at medium- and substrate-related diffraction cut-off edges. We show that spectral sensitivity of medium modes to RI variations is determined by the lattice periodicity in both direct and ATR geometries (similar to 320 nm per RIU change in our case), while substrate mode demonstrates much lower sensitivity. We also show that phase sensitivity of PSLR can exceed 10(5) degrees of phase shift per RIU change and thus outperform the relevant parameter for all other plasmonic sensor counterparts. We finally demonstrate the applicability of surface lattice resonances in plasmonic metamaterial arrays to biosensing using standard streptavidin-biotin affinity model. Combining advantages of nanoscale architectures, including drastic concentration of electric field, possibility of manipulation at the nanoscale etc, and high phase and spectral sensitivities, PSLRs promise the advancement of current state-of-the-art plasmonic biosensing technology toward single molecule label-free detection.