Psychopathology in human immunodeficiency virus infection: lifetime and current assessment.
Psychopathology in human immunodeficiency virus infection: lifetime and current assessment.
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人类免疫缺陷病毒感染的精神病理学：终生和当前评估。
DOI：
10.1016/0010-440x(93)90041-2
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发表时间：
1993
影响因子：
7.3
通讯作者：
RiceJr,RR
中科院分区：
文献类型：
--
作者：
Rosenberger,PH;Bornstein,RA;Nasrallah,HA;Para,MF;Whitaker,CC;Fass,RJ;RiceJr,RR
本研究确定了处于人类免疫缺陷病毒（HIV）感染不同阶段的同性恋或双性恋男性样本的一生和当前精神功能，以解决有关精神病理与HIV感染之间关系的几个问题。艾滋病毒阳性无症状或有症状和艾滋病毒-同性恋或双性恋男子完成心理和健康功能自我报告措施，并参加结构化诊断访谈。获得了有关艾滋病毒相关生活事件及其与发病和精神障碍家族史的潜在关系的其他信息。发现情感和物质使用障碍的终生患病率很高，几乎一半的样本符合这两种障碍的标准。终生情感性障碍诊断与情感性障碍家族史呈正相关。与其他疾病相比，hiv相关事件与情感性障碍的发病或复发关系最为密切。目前发现精神障碍和情绪困扰水平的发生率较低，在不同感染阶段的精神调节程度没有差异。我们得出结论，在HIV阳性和HIV -同性恋样本中，某些类型的精神疾病的终生患病率都很高。精神疾病发病率的增加似乎并不是艾滋病毒感染的结果。然而，在确认感染等与艾滋病毒有关的事件之后，可能会出现疾病发作，特别是情感性障碍。虽然有症状的受试者有更多的躯体困难，但似乎在疾病阶段和情绪困扰程度之间没有关系。
The present study determined lifetime and current psychiatric functioning in a sample of homosexual or bisexual men at various stages of human immunodeficiency virus (HIV) infection in order to address several questions regarding the relationship between psychopathology and HIV infection. HIV+asymptomatic or symptomatic and HIV−homosexual or bisexual men completed self-report measures of psychological and health functioning and participated in structured diagnostic interviews. Additional information regarding HIV-related life events and their potential relationship to onset of disorder and family history of psychiatric disorder were obtained. A high lifetime prevalence of affective and substance use disorder was found, with almost one half of the sample meeting criteria for both disorders. Lifetime affective disorder diagnosis was associated with a positive family history of affective disorder. HIV-related events were most closely associated with onset or recurrence of affective disorder compared with other disorders. Low current rates of psychiatric disorder and levels of emotional distress were found, with no differences in degree of psychiatric adjustment across stage of infection. We conclude that the lifetime prevalence of certain categories of psychiatric disorder is high in both HIV+and HIV−homosexual samples. Increased rates of psychiatric disorders do not appear to be a consequence of HIV infection. However, episodes of illness, particularly affective disorder, may develop following an HIV-related event such as confirmation of infection. Although symptomatic subjects have more somatic difficulties, there appears to be no relationship between stage of illness and level of emotional distress.