Fenestration of the vertebrobasilar junction detected with multidetector computed tomography angiography.
Fenestration of the vertebrobasilar junction detected with multidetector computed tomography angiography.
复制标题
使用多探测器计算机断层扫描血管造影检测椎基底动脉交界处的开窗。
DOI：
10.5603/fm.a2021.0028
复制
发表时间：
2021
影响因子：
1.2
通讯作者：
L. Lazarus
中科院分区：
文献类型：
--
作者：
B. R. Omotoso;R. Harrichandparsad;I. Moodley;K. Satyapal;L. Lazarus
椎基底动脉系统复杂的胚胎起源可能导致广泛的解剖变异。据推测，开窗的形成可能是由于胚胎发生过程中连接纵向神经动脉的桥动脉的退化失败而发生的。椎基底动脉系统的开窗是一种罕见的解剖变异，涉及动脉的管腔分裂，其具有单一的起源成两个独立的平行通道，其在远端重新连接。开孔是接受血管内和侵入性颅内介入治疗的患者的重要解剖结构变体。血管开窗术与动脉瘤、动静脉畸形、神经痛和椎基底动脉缺血有关。我们报告三例开窗在椎基底动脉交界处的一名女性和两名男性患者，分别使用多探测器计算机断层扫描血管造影。在患者中，动脉的开孔段的长度分别为4.41 mm、3.90 mm和5.90 mm。我们的报告是临床上重要的，因为这种解剖变异的存在可能会影响颈部和颅内病变的管理。提高对解剖变异的普遍性的认识有助于无创成像能力的进步。
The complex embryonic origin of the vertebrobasilar system may result in a wide range of anatomical variations. It has been hypothesized that the formation of fenestrations are likely to occur due to the failure of regression of the bridging arteries that connect the longitudinal neural arteries during embryogenesis. Fenestration of the vertebrobasilar system is a rare anatomical variation that involves a luminal division of the artery, that has a single origin into two separate and parallel channels which are rejoined distally. Fenestrations are important anatomical variants in patients undergoing endovascular and invasive intracranial interventions. Vascular fenestration has been associated with aneurysms, arteriovenous malformations, neuralgia, and vertebrobasilar ischemia. We report on three cases of fenestration at the vertebrobasilar junction in one female and two male patients, respectively, using multidetector computed tomography angiography. The length of the fenestrated segment of the artery measured 4.41 mm, 3.90 mm, and 5.90 mm, respectively in the patients. Our report is clinically important as the presence of this anatomical variation may influence the management of cervical and intracranial pathologies. Increased awareness of the prevalence of anatomic variations contributes to the advancement of noninvasive imaging capabilities.