Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline. Part I: Risk Stratification, Shared Decision Making, and Care Options
Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline. Part I: Risk Stratification, Shared Decision Making, and Care Options
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DOI：
10.1016/j.juro.2017.11.095
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发表时间：
2018-03-01
影响因子：
6.6
通讯作者：
Treadwell, Jonathan R.
中科院分区：
文献类型：
--
作者：
Sanda, Martin G.;Cadeddu, Jeffrey A.;Treadwell, Jonathan R.
目的：本指南旨在提供一个按癌症严重程度分层的临床框架，以促进护理决策，并指导实施所选管理方案的细节。本摘要介绍了第一部分的两部分系列致力于临床局限性前列腺癌：AUA/ASTRO/SUO指南讨论的风险分层和护理选项的癌症severity.Materials和Methods：在创建本指南中使用的系统评价是由医疗保健研究和质量机构完成，并通过ECRI研究所的额外补充。该综述包括2007年1月至2014年3月期间发表的文章，并进行了截至2016年8月的更新检索。当存在足够的证据时，特定治疗的证据主体被指定为A（高）、B（中等）或C（低）的强度评级，以支持强、中等或有条件的建议。其他信息作为临床原则和专家意见提供（补充未删节指南中的表2，http：//jurology.com/）。（美国泌尿协会）、ASTRO和SUO（泌尿肿瘤学会）制定了一项基于风险分层临床框架的循证指南，用于管理局限性前列腺癌。该指南试图提高临床医生治疗诊断为局限性前列腺癌患者的能力，但未来试验中更高质量的证据对于提高这些患者的护理水平至关重要。在所有情况下，在选择管理策略时应考虑患者的偏好。
Purpose: This guideline is structured to provide a clinical framework stratified by cancer severity to facilitate care decisions and guide the specifics of implementing the selected management options. The summary presented represents Part I of the two-part series dedicated to Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline discussing risk stratification and care options by cancer severity.Materials and Methods: The systematic review utilized in the creation of this guideline was completed by the Agency for Healthcare Research and Quality and through additional supplementation by ECRI Institute. This review included articles published between January 2007 and March 2014 with an update search conducted through August 2016. When sufficient evidence existed, the body of evidence for a particular treatment was assigned a strength rating of A (high), B (moderate), or C (low) for support of Strong, Moderate, or Conditional Recommendations. Additional information is provided as Clinical Principles and Expert Opinions (table 2 in supplementary unabridged guideline, http://jurology.com/).Results: The AUA (American Urological Association), ASTRO, and SUO (Society of Urologic Oncology) formulated an evidence-based guideline based on a risk stratified clinical framework for the management of localized prostate cancer.Conclusions: This guideline attempts to improve a clinician's ability to treat patients diagnosed with localized prostate cancer, but higher quality evidence in future trials will be essential to improve the level of care for these patients. In all cases, patient preferences should be considered when choosing a management strategy.