Change in optic disk topography after trabeculectomy
Change in optic disk topography after trabeculectomy
复制标题
DOI：
10.1016/s0002-9394(14)70488-x
复制
发表时间：
1996-11-01
影响因子：
4.2
通讯作者：
Weinreb, RN
中科院分区：
文献类型：
--
作者：
Irak, I;Zangwill, L;Weinreb, RN
目得：探讨视盘地形图和眼压之间的关系，小梁切除术前后共焦扫描激光眼底镜检查：49个连续的患者进行小梁切除术在一所大学的青光眼实践的眼睛进行了术前和术后成像使用共焦扫描激光眼底镜（海德堡视网膜断层扫描仪）。在15度视野下获得每例患者一只眼睛的三张图像，术前图像在手术前约2个月获得（平均值+/- SD，2.4 +/- 1.6个月）。术后影像至少在术后3个月获得（平均4.5 ± 2.6个月）。平均术前眼内压、术后眼内压和眼内压变化百分比分别为23.1 ± 6.8 mm Hg、12.7 ± 7.1 mm Hg和43.8% ± 29.9%，发现眼内压下降百分比与杯面积、杯体积和杯/盘面积比下降之间以及眼内压下降百分比与边缘面积、边缘体积、平均高度轮廓、视网膜横截面积和轮廓高度增加之间存在显著相关性（P <0.01）。这些参数中11.7%至31.2%的变异性（R（2））可以用眼内压的百分比变化来解释。地形图变化与眼内压的百分比变化的相关性比与眼内压的平均变化的相关性更强。我们发现眼内压的百分比降低与参考平面高度或最大杯深之间没有关联。视神经地形图的改变与小梁切除术后眼内压的降低有关。
PURPOSE: To investigate the relationship between optic disk topography and intraocular pressure before and after trabeculectomy with confocal scanning laser ophthalmoscopy.METHODS: The eyes of 49 consecutive patients undergoing trabeculectomy at a university based glaucoma practice underwent preoperative and postoperative imaging using a confocal scanning laser ophthalmoscope (Heidelberg Retina Tomograph). Three images of one eye of each patient were obtained with a 15-degree field of view, Preoperative images were obtained approximately 2 months before surgery (mean +/- SD, 2.4 +/- 1.6 months). Postoperative images were obtained at least 3 months after surgery (mean, 4.5 +/- 2.6 months).RESULTS: Mean preoperative intraocular pressure, postoperative intraocular pressure, and percent change in intraocular pressure respectively were 23.1 +/- 6.8 mm Hg, 12.7 +/- 7.1 mm Hg, and 43.8% +/- 29.9%, A significant association (P < .01) was found between percent decrease in intra ocular pressure and decreases in cup area, cup volume, and cup/disk area ratio as well as between percent decrease in intraocular pressure and increases in rim area, rim volume, mean height contour, retinal cross-section area, and height in contour. Between 11.7% and 31.2% of the variability (R(2)) in these parameters was explained by the percent change in intraocular pressure, Topography changes were more strongly associated with percent change than with mean change in intraocular pressure, We found no association between percent decrease in intraocular pressure and reference plane height or maximum cup depth.CONCLUSIONS: Changes in optic nerve topography were associated with reduction in intraocular pressure after trabeculectomy.