Arabidopsis thaliana cdd1 mutant uncouples the constitutive activation of salicylic acid signalling from growth defects.
Arabidopsis thaliana cdd1 mutant uncouples the constitutive activation of salicylic acid signalling from growth defects.
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拟南芥cdd1突变体解开了生长缺陷引起的水杨酸信号的组成型激活。
DOI：
10.1111/j.1364-3703.2011.00717.x
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发表时间：
2011
影响因子：
4.9
通讯作者：
A. Nandi
中科院分区：
文献类型：
--
作者：
Swadhin Swain;Shweta Roy;J. Shah;S. V. Van Wees;C. Pieterse;A. Nandi
具有高活性水杨酸信号通路的拟南芥品种表现出较强的抗病能力，这往往伴随着生长发育缺陷，如叶片上的矮化和自发的坏死病，导致生物量下降。在这篇文章中，我们报道了一个新的拟南芥隐性突变体cdd1(生长发育中没有缺陷的结构性防御1)，它表现出与结构性水杨酸信号相关的增强抗病能力，但没有任何可观察到的多效性表型。在cdd1突变植物中，NPR1(病程相关GENES1的非EXPRESSOR)依赖和NPR1非依赖的水杨酸调节的防御通路都被过度激活，从而增强了对细菌病原体的抗性。然而，功能上的NPR1等位基因是cdd1增强对卵菌病原菌Arabidopsidis的抗性所必需的。水杨酸在cdd1和cdd1npr1突变植株中积累水平升高，是cdd1介导的PR1表达和抗病表型所必需的。此外，我们提供的数据表明，cdd1突变负性调节npr1突变诱导的乙烯/茉莉酸信号的过度激活。
Arabidopsis genotypes with a hyperactive salicylic acid-mediated signalling pathway exhibit enhanced disease resistance, which is often coupled with growth and developmental defects, such as dwarfing and spontaneous necrotic lesions on the leaves, resulting in reduced biomass yield. In this article, we report a novel recessive mutant of Arabidopsis, cdd1 (constitutive defence without defect in growth and development1), that exhibits enhanced disease resistance associated with constitutive salicylic acid signalling, but without any observable pleiotropic phenotype. Both NPR1 (NON-EXPRESSOR OF PATHOGENESIS-RELATED GENES1)-dependent and NPR1-independent salicylic acid-regulated defence pathways are hyperactivated in cdd1 mutant plants, conferring enhanced resistance against bacterial pathogens. However, a functional NPR1 allele is required for the cdd1-conferred heightened resistance against the oomycete pathogen Hyaloperonospora arabidopsidis. Salicylic acid accumulates at elevated levels in cdd1 and cdd1 npr1 mutant plants and is necessary for cdd1-mediated PR1 expression and disease resistance phenotypes. In addition, we provide data which indicate that the cdd1 mutation negatively regulates the npr1 mutation-induced hyperactivation of ethylene/jasmonic acid signalling.
水杨酸和 NPR1 在调节拟南芥细胞生长中的作用。
DOI：
10.1046/j.1365-313x.2001.01158.x
发表时间：
2001
期刊：
The Plant journal : for cell and molecular biology
影响因子：
--
作者：
Vanacker,H;Lu,H;Rate,DN;Greenberg,JT
通讯作者：
Greenberg,JT
影响因子：
7.2
作者：
Ferrari, S;Plotnikova, JM;Ausubel, FM
通讯作者：
Ausubel, FM