RECOMBINANT LEUCOCYTE INTERFERON A INDUCES STEROID-RESISTANT ACUTE VASCULAR REJECTION EPISODES IN RENAL TRANSPLANT RECIPIENTS
RECOMBINANT LEUCOCYTE INTERFERON A INDUCES STEROID-RESISTANT ACUTE VASCULAR REJECTION EPISODES IN RENAL TRANSPLANT RECIPIENTS
复制标题
重组白细胞干扰素 A 会导致肾移植受者出现类固醇抵抗性急性血管排斥反应
DOI：
10.1016/s0140-6736(84)92327-4
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
W. Weimar
中科院分区：
文献类型：
--
作者：
P. Kramer;A. Bijnen;F. T. Kate;J. Jeekel;W. Weimar
In an attempt to determine the safety, tolerance, and prophylactic antiviral activity of high doses of recombinant DNA leucocyte interferon A a double-blind parallel-group study was started in 16 renal transplant recipients. All 16 patients had early rejection episodes. In all 8 interferon-treated patients and 1 placebo-treated patient this rejection, which was of the acute vascular humoral type, was steroid resistant. 3 interferon-treated patients also had transient nephrotic syndrome.
