Ionic and Cellular Basis for Arrhythmogenesis
Ionic and Cellular Basis for Arrhythmogenesis
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DOI：
10.1007/978-1-60761-161-5_3
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发表时间：
2011-01-01
期刊：
影响因子：
--
通讯作者：
Yan, Gan-Xin
中科院分区：
文献类型：
--
作者：
Antzelevitch, Charles;Yan, Gan-Xin
Recent years have witnessed important advances in our appreciation of the mechanisms underlying the development of cardiac arrhythmias. Our understanding of these phenomena has been fueled by innovative advances in the genetic, ionic, and cellular basis for electrical disturbances of the heart. This chapter focuses on our present understanding of ionic and cellular mechanisms responsible for common cardiac arrhythmias The mechanisms responsible for cardiac arrhythmias are divided into two major categories (1) enhanced or abnormal impulse formation and (2) reentry, which occurs when a propagating impulse fails to die out after normal activation of the heart and persists to re-excite the heart after expiration of the refractory period.
