Pregnancy-Associated Deaths Due to Drugs, Suicide, and Homicide in the United States, 2010-2019.

Pregnancy-Associated Deaths Due to Drugs, Suicide, and Homicide in the United States, 2010-2019.
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DOI:
10.1097/aog.0000000000004649
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发表时间:
2022-02-01
影响因子:
7.2
通讯作者:
Goldman-Mellor S
Goldman-Mellor S
中科院分区:
医学2区
文献类型:
--
作者:
Margerison CE;Roberts MH;Gemmill A;Goldman-Mellor S

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估计2010年至2019年全国范围内因毒品,自杀和杀人而导致的妊娠相关死亡的流行率。使用2010年至2019年美国33个州和哥伦比亚特区的死亡证明记录,我们使用妊娠复选框和ICD-10代码确定了妊娠相关死亡,计算了妊娠相关死亡率,并按原因、相对于妊娠的时间、种族或民族以及年龄对死亡进行了分类。在2010年至2019年期间确定的11,782例妊娠相关死亡中,11.4%是由于药物,5.4%是由于自杀,5.4%是由于他杀,而59.3%是由于产科原因,其余18.5%是由于其他原因。与毒品有关的死亡、自杀和他杀占妊娠相关死亡的22.2%。在研究期间,所有三种死亡原因都有所增加,与药物有关的妊娠相关死亡增加了190%。怀孕期间的杀人和与毒品有关的死亡、自杀和产后后期(43至365天)的杀人在这些时期的所有死亡中所占的比例大于这些原因在育龄妇女所有死亡中所占的比例。被确定为非西班牙裔美国印第安人或阿拉斯加原住民的孕妇和产后人群与毒品有关和自杀死亡的风险最高,而被确定为非西班牙裔黑人的人被谋杀的风险最高。因吸毒、自杀和他杀造成的死亡占怀孕期间和产后第一年所有死亡的五分之一以上。与毒品有关的死亡和凶杀在过去十年中有所增加。在这些死亡中存在着严重的种族和族裔不平等。从2010年到2019年,与毒品有关的死亡、自杀和凶杀占美国妊娠相关死亡的22%,与毒品有关的死亡在此期间几乎增加了两倍。
To estimate the prevalence of pregnancy-associated deaths due to drugs, suicide, and homicide nationwide from 2010 to 2019. Using U.S. death certificate records from 2010 to 2019 for 33 states plus the District of Columbia, we identified pregnancy-associated deaths using the pregnancy checkbox and ICD-10 codes, calculated pregnancy-associated death ratios, and categorized deaths by cause, timing relative to pregnancy, race or ethnicity, and age. Of 11,782 pregnancy-associated deaths identified between 2010–2019, 11.4% were due to drugs, 5.4% were due to suicide, and 5.4% were due to homicide, whereas 59.3% were due to obstetric causes and the remaining 18.5% were due to other causes. Drug-related deaths, suicide, and homicide accounted for 22.2% of pregnancy-associated deaths. All three causes of death increased over the study period, with drug-related pregnancy-associated deaths increasing 190%. Homicide during pregnancy and drug-related deaths, suicides, and homicide in the late postpartum period (43 to 365 days) accounted for a larger proportion of all deaths in these time periods than the contribution of these causes to all deaths among women of reproductive age. Pregnant and postpartum people identified as non-Hispanic American Indian or Alaska Native were at highest risk of drug-related and suicide death, whereas people identified as non-Hispanic Black were at highest risk of homicide. Deaths due to drug use, suicide, and homicide constitute over one-fifth of all deaths during pregnancy and the first year postpartum. Drug-related deaths and homicides have increased over the past decade. Substantial racial and ethnic inequities in these deaths exist. Drug-related deaths, suicide, and homicide accounted for 22% of pregnancy-associated deaths in the United States from 2010 through 2019, with drug-related deaths increasing almost two-fold over that period.