Bmc Infectious Diseases Suboptimal Clinical Response to Ciprofloxacin in Patients with Enteric Fever Due to Salmonella Spp. with Reduced Fluoroquinolone Susceptibility: a Case Series

Bmc Infectious Diseases Suboptimal Clinical Response to Ciprofloxacin in Patients with Enteric Fever Due to Salmonella Spp. with Reduced Fluoroquinolone Susceptibility: a Case Series
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Bmc 传染病 沙门氏菌引起的肠热患者对环丙沙星的临床反应不佳。

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发表时间:
2004
期刊:
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影响因子:
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通讯作者:
B. Toye
B. Toye
中科院分区:
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文献类型:
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作者:
R. Slinger;M. Desjardins;A. Mccarthy;K. Ramotar;P. Jessamine;Christiane Guibord;B. Toye

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背景:沙门氏菌属。对氟喹诺酮类药物敏感性降低的患者对这些药物的MIC高于通常的MIC,但仍被NCCLS标准认为是“敏感的”。已经注意到对氟喹诺酮类药物的延迟治疗反应,特别是在由于此类菌株引起的肠热病的情况下。我们回顾了环丙沙星的敏感性和临床结果,我们最近的肠道发热病例。
Background: Salmonella spp. with reduced susceptibility to fluoroquinolones have higher than usual MICs to these agents but are still considered "susceptible" by NCCLS criteria. Delayed treatment response to fluoroquinolones has been noted, especially in cases of enteric fever due to such strains. We reviewed the ciprofloxacin susceptibility and clinical outcome of our recent enteric fever cases.