Medicinal herbs: Drugs or dietary supplements?
Medicinal herbs: Drugs or dietary supplements?
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DOI：
10.1016/s0006-2952(99)00243-9
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发表时间：
2000-02-01
影响因子：
5.8
通讯作者：
Chang, J
中科院分区：
文献类型：
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作者：
Chang, J
评估草药的过程是复杂的，有必要仔细确定一种研究策略，以解决安全和有效的草药产品。尽管将草药的药理活性提炼成适合药物开发的化学物质具有巨大的价值，但另一种方法是开发一种标准化的草药提取物，以产生一致的药理活性。然而，它经常被遗忘，即使在提取物中也有几种有效成分有助于药理作用。有充分的证据表明，草药的提取物一旦在其纯净状态下被分离出来，可以产生与整个草药明显不同的药理作用。本文讨论了一种基于研究的策略，该策略可能部分适用于验证草药的假定健康益处。此外，身体的科学证据，支持药理活性的几种草药简要回顾。(C) 1999 Elsevier Science Inc.；
The process of evaluating medicinal herbs is complex, and there is a need to carefully define a research strategy that addresses a solution to safe and efficacious herbal products. Notwithstanding the immense value of distilling the pharmacological activity of an herb into a chemical suitable for drug development, another approach is to develop a standardized herbal extract that yields consistent pharmacological activity. However, it: frequently is forgotten that even in an extract several active ingredients contribute to the pharmacological action. Sufficient evidence exists to suggest that extracts of medicinal herbs, once isolated in their pure state, can produce pharmacological effects that differ significantly from that of the whole herb. This article discusses a research-based strategy that may be suitable for validating, in part, the putative health benefits of medicinal herbs. Additionally, the body of scientific evidence that underpins the pharmacological activity of several herbs is reviewed briefly. (C) 1999 Elsevier Science Inc.