DIAGNOSIS OF NOSOCOMIAL BACTERIAL PNEUMONIA IN ACUTE, DIFFUSE LUNG INJURY
DIAGNOSIS OF NOSOCOMIAL BACTERIAL PNEUMONIA IN ACUTE, DIFFUSE LUNG INJURY
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DOI：
10.1378/chest.80.3.254
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发表时间：
1981-01-01
期刊：
影响因子：
9.6
通讯作者：
JOHANSON, WG
中科院分区：
文献类型：
--
作者：
ANDREWS, CP;COALSON, JJ;JOHANSON, WG
院内细菌性肺炎作为急性弥漫性肺损伤的并发症，在临床上可能很难与其他病理过程区分开来。为了确定这种情况下通常用于诊断肺炎的结果的可靠性，将细菌性肺炎的临床预测与死后组织学进行了比较。 58% 的研究患者在组织学上存在肺炎，其中 36% 被认为仅有肺损伤。在组织学上仅有弥漫性肺损伤的患者中，20% 的患者经临床评估被认为患有肺炎。总体而言，29%的病例被误诊。在准确确定急性弥漫性肺损伤情况下肺炎预防或治疗措施的效果之前，需要改进诊断技术。
Nosocomial bacterial pneumonia as a complication of acute, diffuse lung injury may be difficult to distinguish clinically from other pathologic processes. To determine the reliability of findings commonly used to diagnose pneumonia in this setting, clinical predictions of bacterial pneumonia were compared with postmortem histology. Pneumonia was present histologically in 58% of the study patients, 36% of whom had been thought to have only lung injury. Among patients who had only diffuse lung injury histologically, 20% were thought to have pneumonia by clinical evaluation. Overall, 29% of cases were misdiagnosed. Improved diagnostic techniques will be required before the efficacy of preventive or therapeutic measures for penumonia in the setting of acute, diffuse lung injury can be accurately determined.