Transitions in pregnancy planning in women recruited for a large prospective cohort study
Transitions in pregnancy planning in women recruited for a large prospective cohort study
复制标题
DOI：
10.1093/humrep/dex065
复制
发表时间：
2017-06-01
影响因子：
6.1
通讯作者：
Baker, D.
中科院分区：
文献类型：
--
作者：
Luderer, U.;Li, T.;Baker, D.
研究问题：妇女在不同强度的怀孕计划之间过渡的比率是否因年龄、婚姻状况和种族/民族而异？简要答复：从低或中等怀孕概率组（PPG）到高PPG的过渡率因年龄、婚姻状况和种族/ethnication.What是已知的：设计前瞻性研究的影响前和围怀孕期暴露对生育力、怀孕和儿童的健康是具有挑战性的，因为在任何特定的时间只有一小部分育龄妇女试图怀孕。据我们所知，目前还没有一项基于人群的前瞻性研究对妊娠计划进行反复评估，这些研究包括在入组时尚未计划妊娠且年龄跨越女性生育年龄范围的女性。从2009年1月至2010年9月，进行了一项纵向研究，对12916名妇女的怀孕概率进行了长达21个月的反复评估参与者/材料，地点，方法：我们分析了来自国家儿童研究先锋研究的数据，这是一项针对儿童及其父母的大规模流行病学出生队列研究的试点研究。在Vanguard研究期间，研究人员在七个地理上分散和多样化的研究地点中的每一个都跟踪了育龄妇女的人口样本，以确定她们何时寻求怀孕，这为前瞻性评估大样本美国妇女怀孕计划的变化提供了独特的机会。在研究进入和每个后续接触，发生在1，3或6个月的间隔取决于PPG，问卷调查被用来评估怀孕计划的行为维度，以分配妇女低，中，高non-tryer和高tryer PPGs.Main结果和机会的作用：怀孕的粗率增加较高的分配PPG，验证工具的效用。初始PPG和从低或中等PPG转变为较高PPG或妊娠的概率随年龄、婚姻状况和人种/种族而变化。25岁至
STUDY QUESTION: Do the rates at which women transition among different intensities of pregnancy planning vary with age, marital status and race/ethnicity?SUMMARY ANSWER: Rates of transition from low or moderate pregnancy probability groups (PPGs) to higher PPGs vary by age, marital status and race/ethnicity.WHAT IS KNOWN ALREADY: The design of prospective studies of the effects of pre- and peri-conception exposures on fecundity, pregnancy and children's health is challenging because at any specific time only a small percentage of reproductive age women is attempting to conceive. To our knowledge, there has been no population-based, prospective study that repeatedly assessed pregnancy planning, which included women who were not already planning pregnancy at enrollment and whose ages spanned the female reproductive age range.STUDY DESIGN, SIZE, DURATION: A longitudinal study was carried out that repeatedly assessed pregnancy probability in 12 916 women for up to 21 months from January 2009 to September 2010.PARTICIPANTS/MATERIALS, SETTING, METHOD: We analyzed data from the National Children's Study Vanguard Study, a pilot study for a large-scale epidemiological birth cohort study of children and their parents. During the Vanguard Study, investigators followed population-based samples of reproductive age women in each of seven geographically dispersed and diverse study locations over time to identify when they sought to become pregnant, providing a unique opportunity to prospectively assess changes in pregnancy planning in a large sample of US women. At study entry and each follow-up contact, which occurred at 1, 3 or 6 month intervals depending on PPG, a questionnaire was used to assess behavior dimensions of pregnancy planning to assign women to low, moderate, high non-tryer and high tryer PPGs.MAIN RESULTS AND THE ROLE OF CHANCE: Crude rates of pregnancy increased with higher assigned PPG, validating the utility of the instrument. The initial PPG and probabilities of transitioning from low or moderate PPG to higher PPG or pregnancy varied with age, marital status and race/ethnicity. Women aged 25 to