Chemistry of Zerumbone. 2. Regulation of Ring Bond Cleavage and Unique Antibacterial Activities of Zerumbone Derivatives
Chemistry of Zerumbone. 2. Regulation of Ring Bond Cleavage and Unique Antibacterial Activities of Zerumbone Derivatives
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Zerumbone 的化学。
DOI：
10.1271/bbb.65.2193
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
T. Okamoto
中科院分区：
文献类型：
--
作者：
T. Kitayama;Kaneyoshi Yamamoto;R. Utsumi;M. Takatani;R. K. Hill;Y. Kawai;S. Sawada;T. Okamoto
对十一元环状倍半萜烯、姜酮（Zingiber zerumbet Smith）的主要成分的化学的进一步研究揭示了一种新的选择性环氧化过程，这是新的 Favorskii 引发的双环收缩的进一步例子，以及姜酮二溴化物衍生物的区域特异性断裂。几种姜酮衍生物被发现是革兰氏阳性菌生长的选择性抑制剂。
Further investigation of the chemistry of the elevenmembered cyclic sesquiterpene, zerumbone, the major component of the wild ginger, Zingiber zerumbet Smith, has revealed a new selective epoxidation process, a further example of a novel Favorskii-initiated double ring contraction, and a regiospecific fragmentation of zerumbone dibromide derivatives. Several zerumbone derivatives were found to be selective inhibitors of the growth of Gram-positive bacteria.