Syringe-pump-induced fluctuation in all-aqueous microfluidic system implications for flow rate accuracy
Syringe-pump-induced fluctuation in all-aqueous microfluidic system implications for flow rate accuracy
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DOI：
10.1039/c3lc51176f
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发表时间：
2014-01-01
期刊：
影响因子：
6.1
通讯作者：
Shum, Ho Cheung
中科院分区：
文献类型：
--
作者：
Li, Zida;Mak, Sze Yi;Shum, Ho Cheung
报道了一种利用具有超低界面张力的液-液系统来显示微流控流中注射泵引起的微小波动的新方法。通过比较界面处观察到的脉动频率和步进电机的脉动频率，我们证明了泵内的步进电机是微流体流波动的来源。我们还量化了不同流量、不同直径的注射器和不同推进距离的注射泵在不同速度下引起的波动。我们的工作提供了一种方法来预测驱动注射泵在微流体系统中引起的波动的频率，并表明注射泵可能是微流体流动中波动的来源，从而导致所产生的液滴的多分散性。
We report a new method to display the minute fluctuations induced by syringe pumps on microfluidic flows by using a liquid-liquid system with an ultralow interfacial tension. We demonstrate that the stepper motor inside the pump is a source of fluctuations in microfluidic flows by comparing the frequencies of the ripples observed at the interface to that of the pulsation of the stepper motor. We also quantify the fluctuations induced at different flow rates, using syringes of different diameters, and using different syringe pumps with different advancing distances per step. Our work provides a way to predict the frequency of the fluctuation that the driving syringe pump induces on a microfluidic system and suggests that syringe pumps can be a source of fluctuations in microfluidic flows, thus contributing to the polydispersity of the resulting droplets.