Combined Angiography and Late Gadolinium Enhancement Acquisition to Improve Assessment of Pulmonary Vein Isolation for Atrial Fibrillation.
Combined Angiography and Late Gadolinium Enhancement Acquisition to Improve Assessment of Pulmonary Vein Isolation for Atrial Fibrillation.
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DOI：
10.1002/jmri.25771
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发表时间：
2018-03
期刊：
影响因子：
--
通讯作者：
Oshinski JN
中科院分区：
文献类型：
--
作者：
Lam A;Okene E;Parikh A;Zhong X;Tejada T;Hoskins M;Lloyd M;Oshinski JN
目的开发一种共享的K空间MRI序列，该序列结合了血管造影和晚期Gd增强(LGE)采集，以改进房壁分割和疤痕识别，并开发一种新的可视化方法，用于量化房颤消融治疗后肺静脉瘢痕环绕。建立了共享K空间(SHARK)序列，并在3T对11例冷冻消融术后患者的左心房进行成像。评估血管造影和LGE采集之间共享k空间对SCAR准确性的影响。左房壁被分割，每一个肺静脉(PV)口周围的点被投射到一个牛眼上，以定量比较PV的包围。改变用于量化包围度的参数以进行敏感性分析。与使用全套k空间相比，只有当共享75%k空间时，才有显著差异(p=0.014)，当共享50%k空间时，识别瘢痕的敏感度和特异度达到90%。在患者中，与左侧静脉相比，右侧静脉显示出更多的受试者间包围性差异。左室前下部100°始终被包绕，双侧右室上段消融仅6例。应用SHARK序列结合血管造影和LGE成像进行房壁分割和瘢痕识别。PV牛眼可以量化和定位围绕PV的包围。左肺静脉较右肺静脉显示更多的瘢痕包围量和更少的变异。
To develop a Shared K-space MRI sequence that combines angiographic and late gadolinium enhancement (LGE) acquisitions to improve atrial wall segmentation and scar identification, and to develop a novel visualization method that quantifies scar encirclement of pulmonary veins post-ablation treatment for atrial fibrillation. A Shared K-space (SharK) sequence was developed and used at 3T to image the left atrium in eleven patients post-cryoballoon ablation. The effects of sharing k-space between the angiographic and LGE acquisitions on the accuracy of scar were assessed. The left atrial wall was segmented and points about each pulmonary vein (PV) ostia were projected onto a bullseye to quantitatively compare PV encirclement. The parameters used to quantify encirclement were varied to perform a sensitivity analysis. Compared to using a complete set of k-space, total atrial scar differences were significant only when sharing > 75% k-space (p=0.014), and 90% sensitivity and specificity for identifying scar was achieved when sharing 50% k-space. In patients, the right PVs showed more inter-subject variance in encirclement compared to the left PVs. A 100° anteroinferior portion of the left PVs was always encircled while the superior segments of both right PVs was ablated in only 6/11 patients. A SharK sequence was developed to combine angiographic and LGE imaging for atrial wall segmentation and scar identification. The PV bullseye quantifies and localizes encirclement about the PVs. The left PVs showed higher amount of scar encirclement and less variability compared to the right PVs.
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影响因子：
5.5
作者：
Taclas, Jason E.;Nezafat, Reza;Peters, Dana C.
通讯作者：
Peters, Dana C.
DOI：
10.1016/j.jcmg.2015.10.015
发表时间：
2016-02
期刊：
JACC. Cardiovascular imaging
影响因子：
--
作者：
Khurram IM;Habibi M;Gucuk Ipek E;Chrispin J;Yang E;Fukumoto K;Dewire J;Spragg DD;Marine JE;Berger RD;Ashikaga H;Rickard J;Zhang Y;Zipunnikov V;Zimmerman SL;Calkins H;Nazarian S
通讯作者：
Nazarian S
影响因子：
24
作者：
McGann C;Kholmovski E;Blauer J;Vijayakumar S;Haslam T;Cates J;DiBella E;Burgon N;Wilson B;Alexander A;Prastawa M;Daccarett M;Vergara G;Akoum N;Parker D;MacLeod R;Marrouche N
通讯作者：
Marrouche N
影响因子：
0.9
作者：
Harrison, James L.;Whitaker, John;O'Neill, Mark D.
通讯作者：
O'Neill, Mark D.
影响因子：
19.7
作者：
Peters, Dana C.;Wylie, John V.;Manning, Warren J.
通讯作者：
Manning, Warren J.