Is Fluid Consumption Necessary for the Formation of Context-Illness Associations? An Evaluation Using Consumption and Blocking Tests

Is Fluid Consumption Necessary for the Formation of Context-Illness Associations? An Evaluation Using Consumption and Blocking Tests
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液体消耗对于形成背景疾病关联是必要的吗?

DOI:
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发表时间:
1998
期刊:
影响因子:
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通讯作者:
Marcial Rodríguez
Marcial Rodríguez
中科院分区:
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文献类型:
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作者:
M. Symonds;G. Hall;Matías López;Ignacio Loy;Alfredo Ramos;Marcial Rodríguez

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在两个实验中,大鼠经历了两种不同的环境,其中一种是注射氯化锂,另一种则没有。一半的受试者被允许在锂配对的情况下喝水,而其余的则没有液体。在实验1的测试阶段,所有受试者都在上下文中获得蔗糖溶液。那些人的水已提供条件反射试验显示出实质性的抑制蔗糖消费的目标背景下,相对于nonpoisoned上下文。在训练期间没有获得水的受试者中不存在这种效果。然而,实验2,采用了阻断程序作为测试的关联强度的背景下,发现证据的上下文条件反射在这两组受试者。我们认为,阻塞程序提供了一个更准确的评估所获得的关联强度的上下文刺激比传统的消费测试,因此能够揭示上下文条件反射的发生,即使在受试者没有获得流体在训练过程中。
Abstract In two experiments, rats experienced two distinctive contexts, one of which was followed by an injection of lithium chloride and the other not. Half the subjects were allowed to consume water in the lithium-paired context, whereas for the remainder no fluid was made available. In the test phase of Experiment 1 all subjects received access to sucrose solution in the contexts. Those for whom water had been available on conditioning trials showed substantial suppression of sucrose consumption in the target context, relative to the nonpoisoned context. This effect was absent in the subjects that had not received access to water during training. Experiment 2, however, which employed a blocking procedure as the test for the associative strength of the context, found evidence for contextual conditioning in both groups of subjects. We argue that the blocking procedure provides a more accurate assessment of the associative strength acquired by contextual stimuli than does the traditional consumption test and is thus able to reveal the occurrence of context conditioning even in subjects given no access to fluid during training.