Arterial spin-labeling in routine clinical practice, part 2: hypoperfusion patterns.

Arterial spin-labeling in routine clinical practice, part 2: hypoperfusion patterns.
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DOI:
10.3174/ajnr.a1033
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发表时间:
2008-08
期刊:
AJNR. American journal of neuroradiology
影响因子:
--
通讯作者:
Maldjian JA
Maldjian JA
中科院分区:
其他
文献类型:
--
作者:
Deibler AR;Pollock JM;Kraft RA;Tan H;Burdette JH;Maldjian JA

文献摘要

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动脉自旋标记(ASL)是一种功能强大的灌注成像技术,能够在广泛的疾病状态下快速显示全局或局部范围内的低灌注和高灌注。了解血流的病理生理变化和序列固有的常见伪影,可以在作为常规临床成像方案的一部分进行时准确解释ASL。尚未描述在大量临床人群中常规应用ASL灌注成像期间遇到的低灌注模式。这篇综述文章的目的是说明我们的经验与一个异质性收集的ASL灌注情况下,并描述模式的低灌注。在1年的时间内,进行了超过3000次脉冲ASL手术,作为常规临床脑MR成像评价的组成部分,在1.5和3T下进行。这些图像进行了审查,在各种正常和疾病状态下的图像质量和低灌注模式。
Arterial spin-labeling (ASL) is a powerful perfusion imaging technique capable of quickly demonstrating both hypo- and hyperperfusion on a global or localized scale in a wide range of disease states. Knowledge of pathophysiologic changes in blood flow and common artifacts inherent to the sequence allows accurate interpretation of ASL when performed as part of a routine clinical imaging protocol. Patterns of hypoperfusion encountered during routine application of ASL perfusion imaging in a large clinical population have not been described. The objective of this review article is to illustrate our experience with a heterogeneous collection of ASL perfusion cases and describe patterns of hypoperfusion. During a period of 1 year, more than 3000 pulsed ASL procedures were performed as a component of routine clinical brain MR imaging evaluation at both 1.5 and 3T. These images were reviewed with respect to image quality and patterns of hypoperfusion in various normal and disease states.