Relationship of cardiovascular reactivity and anger expression to serum lipid concentrations in healthy young men.

Relationship of cardiovascular reactivity and anger expression to serum lipid concentrations in healthy young men.
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健康年轻男性心血管反应性和愤怒表达与血清脂质浓度的关系。

DOI:
10.1016/0022-3999(93)90033-c
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发表时间:
1993
影响因子:
4.7
通讯作者:
Manuck,SB
Manuck,SB
中科院分区:
医学3区
文献类型:
--
作者:
Waldstein,SR;Polefrone,JM;Bachen,EA;Muldoon,MF;Kaplan,JR;Manuck,SB

文献摘要

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在63名健康的年轻成年男性中,研究了行为诱发的心血管反应性、愤怒表达的首选模式和血脂浓度之间的关系。受试者来自三项研究,每项研究均评估实验室应激源对心血管的反应。所有参与者都完成了Spielberger愤怒表达量表,并提供了空腹血液样本进行血脂测定。通过荟萃分析程序计算,心率反应性的无基线测量与高密度脂蛋白胆固醇(HDL-C)浓度之间存在显著负相关(r=-0.26,p = 0.05)。然而,没有发现先前报道的心血管反应性与血清总胆固醇(TSC)升高之间的关系。此外,在自我报告的外向表达愤怒倾向的测量中得分高的男性的HDL-C浓度显著高于得分低的男性(r= 0.30,p = 0.02);当受试者按心血管反应性水平分层时,这种关系仅在对急性精神应激表现出最大幅度心率和血压反应的受试者中明显。
The relationship between behaviorally evoked cardiovascular reactivity, preferred mode of anger expression, and serum lipid concentrations was examined in 63 healthy, young adult males. Subjects derived from three studies, each evaluating cardiovascular response to laboratory stressors. All participants completed the Spielberger Anger Expression Scale and provided fasting blood samples for lipid determinations. A significant negative correlation, calculated by meta-analytic procedures, was noted between a baseline-free measure of heart rate reactivity and high density lipoprotein-cholesterol (HDL-C) concentrations (r= -0.26,p= 0.05). However, the previously reported relationship between cardiovascular reactivity and elevated total serum cholesterol (TSC) was not found. Additionally, men scoring high on a self-report measure of the tendency to express anger outwardly had significantly higher HDL-C concentrations that men scoring low on this measure (r= 0.30,p= 0.02); when subjects were stratified by level of cardiovascular reactivity, this relationship was apparent only among those showing the greatest magnitude of heart rate and blood pressure responses to acute mental stress.