Breaking up MTDH-SND1 to break down metastasis.
Breaking up MTDH-SND1 to break down metastasis.
复制标题
破坏 MTDH-SND1 以破坏转移。
DOI:
10.1038/s43018-021-00320-7
复制
发表时间:
2022
期刊:
影响因子:
22.7
通讯作者:
Ganesh,Karuna
中科院分区:
文献类型:
--
作者:
Jiang,Qingwen;Ganesh,Karuna
Although many potential targets have been identified, effective, specific therapies for metastatic cancers are still lacking. Two studies now identify small-molecule inhibitors of MTDH–SND1 interaction that potently suppress breast cancer progression and metastasis via concerted cancer-cell-autonomous effects and immune modulation.