Neurotoxin Production by a Chloromonad Fibrocapsa japonica (Raphidophyceae)
Neurotoxin Production by a Chloromonad Fibrocapsa japonica (Raphidophyceae)
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日本纤维藻氯单胞菌（Raphidophyceae）产生神经毒素
DOI：
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发表时间：
1996
期刊：
影响因子：
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通讯作者：
Y. Onoue
中科院分区：
文献类型：
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作者：
Saleha Khan;O. Arakawa;Y. Onoue
本文研究了一种产赤潮的日本绿球藻（Toriumi和Takano）的鱼类毒性和毒素组成。随着球形细胞数量的增加，鞭毛虫在对数生长中期毒性最高，在稳定期毒性最低。通过对F的分析，初步鉴定出五种神经毒性组分FjTx-I、FjTx-II、FjTx-IIIa、FjTx-IIIb和FjTx-IV，分别对应于短尾寒武螺毒素组分PbTx-1、PbTx-2、PbTx-9、PbTx-3和氧化型PbTx-2。日本毒素的薄层色谱和高效液相色谱分析。各组分的含量随培养物的年龄和生长阶段而波动。在五种毒性成分中，FjTx-II每细胞的产量在对数期和稳定期都是最高的。
The ichthyotoxicity and toxin composition of a red-tide producing chloromonad Fibrocapsa japonica (Toriumi and Takano) were examined. The flagellate showed the highest toxicity in mid-logarithmic phase and the lowest in the stationary phase with increased number of spherical-shaped cells. Five neurotoxic components, FjTx-I, FjTx-II, FjTx-IIIa, FjTx-IIIb and FjTx-IV, which corresponded to brevetoxin components, PbTx-1, PbTx-2, PbTx-9, PbTx-3 and oxidized PbTx-2 were tentatively identified from analysis of F. japonica toxins on TLC and HPLC. The quantity of each component fluctuated with the age and growth stage of the culture. Among the five toxic components the yield of FjTx-II per cell was highest in both logarithmic and stationary phases.