International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia
International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia
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DOI：
10.1183/13993003.00582-2017
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发表时间：
2017-09-01
影响因子：
24.3
通讯作者：
Wunderink, Richard
中科院分区：
文献类型：
--
作者：
Torres, Antoni;Niederman, Michael S.;Wunderink, Richard
关于医院获得性肺炎（HAP）和呼吸机相关性肺炎（VAP）的最新欧洲指南和工作组报告发表于近10年前。此后，HAP和VAP的进一步随机临床试验已经进行，并获得了新的信息。流行病学、诊断、经验性治疗、对治疗的反应、新抗生素或新形式的抗生素给药和疾病预防的研究已经改变了旧的模式。此外，欧洲和美国的方法之间的重要差异已经变得明显。欧洲呼吸学会发起了一个项目，制定新的HAP和VAP国际指南。其他欧洲学会，包括欧洲重症监护医学学会和欧洲临床微生物学和传染病学会，应邀参加并任命了代表。拉丁美洲胸科协会也受到邀请，共有15名专家和两名方法学家组成了小组。来自美国的三位专家也被邀请（Michael S.应用GRADE（建议、评估、发展和评价的分级）方法，专家组选择了7个皮科（人群干预比较结果）问题，这些问题产生了一系列HAP/VAP诊断、治疗和预防的建议。
The most recent European guidelines and task force reports on hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 years ago. Since then, further randomised clinical trials of HAP and VAP have been conducted and new information has become available. Studies of epidemiology, diagnosis, empiric treatment, response to treatment, new antibiotics or new forms of antibiotic administration and disease prevention have changed old paradigms. In addition, important differences between approaches in Europe and the USA have become apparent.The European Respiratory Society launched a project to develop new international guidelines for HAP and VAP. Other European societies, including the European Society of Intensive Care Medicine and the European Society of Clinical Microbiology and Infectious Diseases, were invited to participate and appointed their representatives. The Latin American Thoracic Association was also invited.A total of 15 experts and two methodologists made up the panel. Three experts from the USA were also invited (Michael S. Niederman, Marin Kollef and Richard Wunderink).Applying the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) methodology, the panel selected seven PICO (population-intervention-comparison-outcome) questions that generated a series of recommendations for HAP/VAP diagnosis, treatment and prevention.