Inhibition and excitation of neck and shoulder muscles during unilateral electrical stimulation of the rat neostriatum.
Inhibition and excitation of neck and shoulder muscles during unilateral electrical stimulation of the rat neostriatum.
复制标题
单侧电刺激大鼠新纹状体期间颈部和肩部肌肉的抑制和兴奋。
DOI：
10.1016/0166-4328(88)90002-2
复制
发表时间：
1988
影响因子：
2.7
通讯作者：
Kelland,DZ
中科院分区：
文献类型：
--
作者：
Kelland,MD;Asdourian,D;Kelland,DZ
用电刺激成年雄性大鼠尾壳核(Cd-Ptt)的方法，观察Cd-Ptt对斜方肌、颈二头肌、头直肌和背斜角肌的控制作用。单侧Cd-Pt刺激导致肌肉反应模式，其特点是同侧自发活动立即被抑制，随后对侧活动被激发。黑质网状部的病变阻断了4块肌肉中的3块肌肉的兴奋，而苍白球病变的结果不明确。然而，额顶运动皮质的控制性消融阻断了所有肌肉的兴奋，海人酸损毁Cd-PT对兴奋没有影响，这表明肌肉活动的兴奋只能归因于刺激穿过该区域的皮质分离纤维(即Cd-PT)。自发活动的抑制似乎确实归因于对镉-铂的刺激。
Electrical stimulation of the caudate-putamen (Cd-Pt) in anesthetized adult male rats was used to determine the nature and extent of the control exerted by the Cd-Pt over the following neck and shoulder muscles: the trapezius, biventer cervicis, rectus capitis and scalenus dorsalis. Unilateral Cd-Pt stimulation resulted in a pattern of muscle responses marked by immediate inhibition of ipsilateral spontaneous activity and subsequent excitation of contralateral activity. Lesions of the substantia nigra pars reticulata blocked the excitation in 3 of the 4 muscles, while globus pallidus lesions had equivocal results. However, control ablations of the frontoparietal motor cortex, which blocked excitation in all muscles, and kainic acid lesions of the Cd-Pt, which had no effect on excitation, suggested that the excitation of muscle activity can only be attributed to the stimulation of corticofugal fibers passing through this region (i.e. the Cd-Pt). The inhibition of spontaneous activity does appear to be attributable to stimulation of the Cd-Pt.